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10.2302/kjm.2021-0005-OA http://scihub22266oqcxt.onion/10.2302/kjm.2021-0005-OA 33853975!ä!33853975 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Keio+J+Med 2021 ; 70 (2): 44-50 Nephropedia Template TP {{tp|p=33853975|t=2021. Identification of B 1 346 Lineage of SARS-CoV-2 in Japan: Genomic Evidence of Re-entry of Clade 20C |pdf=|usr=}}{{33853975}} gab.com Text Identification of B 1 346 Lineage of SARS-CoV-2 in Japan: Genomic Evidence of Re-entry of Clade 20C JO: Keio J Med http://www.kidney.de/pget.php?&tw=1&pmid=33853975 #FOAvip SARS-CoV-2 whole-genome sequencing of samples from COVID-19 patients is useful for informing infection control. Datasets of these genomes assembled from multiple hospitals can give critical clues to regional or national trends in infection. Herein, we report a lineage summary based on data collected from hospitals located in the Tokyo metropolitan area. We performed SARS-CoV-2 whole-genome sequencing of specimens from 198 patients with COVID-19 at 13 collaborating hospitals located in the Kanto region. Phylogenetic analysis and fingerprinting of the nucleotide substitutions were performed to differentiate and classify the viral lineages. More than 90% of the identified strains belonged to Clade 20B, which has been prevalent in European countries since March 2020. Only two lineages (B.1.1.284 and B.1.1.214) were found to be predominant in Japan. However, one sample from a COVID-19 patient admitted to a hospital in the Kanto region in November 2020 belonged to the B.1.346 lineage of Clade 20C, which has been prevalent in the western United States since November 2020. The patient had no history of overseas travel or any known contact with anyone who had travelled abroad. Consequently, the Clade 20C strain belonging to the B.1.346 lineage appeared likely to have been imported from the western United States to Japan across the strict quarantine barrier. B.1.1.284 and B.1.1.214 lineages were found to be predominant in the Kanto region, but a single case of the B.1.346 lineage of clade 20C, probably imported from the western United States, was also identified. These results illustrate that a decentralized network of hospitals offers significant advantages as a highly responsive system for monitoring regional molecular epidemiologic trends. Twit Text FOAVip Identification of B 1 346 Lineage of SARS-CoV-2 in Japan: Genomic Evidence of Re-entry of Clade 20C ????Keio J Med http://www.kidney.de/pget.php?&tw=1&pmid=33853975 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33853975 #FOAvip English Wikipedia <ref>{{Cite pmid|33853975}}</ref> Identification of B 1 346 Lineage of SARS-CoV-2 in Japan: Genomic Evidence of Re-entry of Clade 20C #MMPMID33853975 Abe K; Shimura T; Takenouchi T; Iwasaki YW; Ishizu H; Uwamino Y; Uno S; Gotoh J; Tachikawa N; Takeuchi Y; Katayama J; Nozaki H; Fujii S; Seki S; Nakamura M; Uda K; Misumi T; Ishihara J; Yamada K; Kanai T; Murai S; Araki K; Ebihara T; Siomi H; Hasegawa N; Kitagawa Y; Amagai M; Suematsu M; Kosaki K Keio J Med 2021[Jun]; 70 (2): 44-50 PMID33853975show ga SARS-CoV-2 whole-genome sequencing of samples from COVID-19 patients is useful for informing infection control. Datasets of these genomes assembled from multiple hospitals can give critical clues to regional or national trends in infection. Herein, we report a lineage summary based on data collected from hospitals located in the Tokyo metropolitan area. We performed SARS-CoV-2 whole-genome sequencing of specimens from 198 patients with COVID-19 at 13 collaborating hospitals located in the Kanto region. Phylogenetic analysis and fingerprinting of the nucleotide substitutions were performed to differentiate and classify the viral lineages. More than 90% of the identified strains belonged to Clade 20B, which has been prevalent in European countries since March 2020. Only two lineages (B.1.1.284 and B.1.1.214) were found to be predominant in Japan. However, one sample from a COVID-19 patient admitted to a hospital in the Kanto region in November 2020 belonged to the B.1.346 lineage of Clade 20C, which has been prevalent in the western United States since November 2020. The patient had no history of overseas travel or any known contact with anyone who had travelled abroad. Consequently, the Clade 20C strain belonging to the B.1.346 lineage appeared likely to have been imported from the western United States to Japan across the strict quarantine barrier. B.1.1.284 and B.1.1.214 lineages were found to be predominant in the Kanto region, but a single case of the B.1.346 lineage of clade 20C, probably imported from the western United States, was also identified. These results illustrate that a decentralized network of hospitals offers significant advantages as a highly responsive system for monitoring regional molecular epidemiologic trends. |*Genome, Viral[MESH] |COVID-19/*virology[MESH] |Humans[MESH] |Phylogeny[MESH] |SARS-CoV-2/*genetics[MESH]Identification of B 1 346 Lineage of SARS-CoV-2 in Japan: Genomic Evid(epmc).pdf DeepDyve Pubget Overpricing