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10.5578/tt.20219909

http://scihub22266oqcxt.onion/10.5578/tt.20219909
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33853308!ä!33853308

suck abstract from ncbi


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pmid33853308      Tuberk+Toraks 2021 ; 69 (1): 74-83
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  • Agir COVID-19 enfeksiyonunda tosilizumab'in etkinligi: Guncel calismalarin derlemes #MMPMID33853308
  • Yakar HI; Pazarli AC; Inonu Koseoglu H; Kanbay A
  • Tuberk Toraks 2021[Mar]; 69 (1): 74-83 PMID33853308show ga
  • The COVID-19 outbreak that spread in December 2019 has caused the death of millions of people in a short time. Many studies published recently have shown that many cytokines (interleukin (IL) IL-1, IL-2, IL-6, TNF and IFN-) are significantly increased in COVID-19 patients with pneumonia, and especially IL-6 in combination with other cytokines has shown to be the main cause of the cytokine storm. Since IL-6 level is associated with clinical worsening in COVID-19 patients, anti-IL-6 therapy is seen as a promising treatment. Tocilizumab, a widely used IL-6 antagonist, was approved by the FDA in 2017 for Cytokine Storm Syndrome (CSS). Its addition to the treatment in COVID19 patients with increased blood IL-6 levels and oxygen saturation.
  • |*COVID-19 Drug Treatment[MESH]
  • |*SARS-CoV-2[MESH]
  • |Antibodies, Monoclonal, Humanized/*therapeutic use[MESH]
  • |Biomarkers/blood[MESH]
  • |COVID-19/blood/epidemiology[MESH]
  • |Cytokines/blood[MESH]
  • |Humans[MESH]


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