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10.1016/j.biopha.2021.111561 http://scihub22266oqcxt.onion/10.1016/j.biopha.2021.111561 33848775!ä!33848775 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomed+Pharmacother 2021 ; 139 (ä): 111561 Nephropedia Template TP {{tp|p=33848775|t=2021. Pharmacological and clinical application of heparin progress: An essential drug for modern medicine |pdf=|usr=}}{{33848775}} gab.com Text Pharmacological and clinical application of heparin progress: An essential drug for modern medicine JO: Biomed Pharmacother http://www.kidney.de/pget.php?&tw=1&pmid=33848775 #FOAvip Heparin is the earliest and most widely used anticoagulant and antithrombotic drug that is still used in a variety of clinical indications. Since it was discovered in 1916, after more than a century of repeated exploration, heparin has not been replaced by other drugs, but a great progress has been made in its basic research and clinical application. Besides anticoagulant and antithrombotic effects, heparin also has antitumor, anti-inflammatory, antiviral, and other pharmacological activities. It is widely used clinically in cardiovascular and cerebrovascular diseases, lung diseases, kidney diseases, cancer, etc., as the first anticoagulant medicine in COVID-19 exerts anticoagulant, anti-inflammatory and antiviral effects. At the same time, however, it also leads to a lot of adverse reactions, such as bleeding, thrombocytopenia, elevated transaminase, allergic reactions, and others. This article comprehensively reviews the modern research progress of heparin compounds; discusses the structure, preparation, and adverse reactions of heparin; emphasizes the pharmacological activity and clinical application of heparin; reveals the possible mechanism of the therapeutic effect of heparin in related clinical applications; provides evidence support for the clinical application of heparin; and hints on the significance of exploring the wider application fields of heparin. Twit Text FOAVip Pharmacological and clinical application of heparin progress: An essential drug for modern medicine ????Biomed Pharmacother http://www.kidney.de/pget.php?&tw=1&pmid=33848775 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33848775 #FOAvip English Wikipedia <ref>{{Cite pmid|33848775}}</ref> Pharmacological and clinical application of heparin progress: An essential drug for modern medicine #MMPMID33848775 Qiu M; Huang S; Luo C; Wu Z; Liang B; Huang H; Ci Z; Zhang D; Han L; Lin J Biomed Pharmacother 2021[Jul]; 139 (ä): 111561 PMID33848775show ga Heparin is the earliest and most widely used anticoagulant and antithrombotic drug that is still used in a variety of clinical indications. Since it was discovered in 1916, after more than a century of repeated exploration, heparin has not been replaced by other drugs, but a great progress has been made in its basic research and clinical application. Besides anticoagulant and antithrombotic effects, heparin also has antitumor, anti-inflammatory, antiviral, and other pharmacological activities. It is widely used clinically in cardiovascular and cerebrovascular diseases, lung diseases, kidney diseases, cancer, etc., as the first anticoagulant medicine in COVID-19 exerts anticoagulant, anti-inflammatory and antiviral effects. At the same time, however, it also leads to a lot of adverse reactions, such as bleeding, thrombocytopenia, elevated transaminase, allergic reactions, and others. This article comprehensively reviews the modern research progress of heparin compounds; discusses the structure, preparation, and adverse reactions of heparin; emphasizes the pharmacological activity and clinical application of heparin; reveals the possible mechanism of the therapeutic effect of heparin in related clinical applications; provides evidence support for the clinical application of heparin; and hints on the significance of exploring the wider application fields of heparin. |*Drugs, Essential[MESH] |Animals[MESH] |Anticoagulants/*pharmacology/*therapeutic use[MESH] |COVID-19 Drug Treatment[MESH] |Cardiovascular Diseases/drug therapy[MESH] |Cerebrovascular Disorders/drug therapy[MESH] |Fibrinolytic Agents/*pharmacology/*therapeutic use[MESH] |Heparin/*pharmacology/*therapeutic use[MESH] |Humans[MESH] |Kidney Diseases/drug therapy[MESH]Pharmacological and clinical application of heparin progress: An essen(epmc).pdf DeepDyve Pubget Overpricing