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10.1016/j.biopha.2021.111578

http://scihub22266oqcxt.onion/10.1016/j.biopha.2021.111578
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33848774!8023207!33848774
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suck abstract from ncbi


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pmid33848774      Biomed+Pharmacother 2021 ; 139 (ä): 111578
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  • Will curcumin nanosystems be the next promising antiviral alternatives in COVID-19 treatment trials? #MMPMID33848774
  • Dourado D; Freire DT; Pereira DT; Amaral-Machado L; N Alencar E; de Barros ALB; Egito EST
  • Biomed Pharmacother 2021[Jul]; 139 (ä): 111578 PMID33848774show ga
  • The COVID-19 has become of striking interest since the number of deaths is constantly rising all over the globe, and the search for an efficient treatment is more urgent. In light of this worrisome scenario, this opinion review aimed to discuss the current knowledge about the potential role of curcumin and its nanostructured systems on the SARS-CoV-2 targets. From this perspective, this work demonstrated that curcumin urges as a potential antiviral key for the treatment of SARS-CoV-2 based on its relation to the infection pathways. Moreover, the use of curcumin-loaded nanocarriers for increasing its bioavailability and therapeutic efficiency was highlighted. Additionally, the potential of the nanostructured systems by themselves and their synergic action with curcumin on molecular targets for viral infections have been explored. Finally, a viewpoint of the studies that need to be carried out to implant curcumin as a treatment for COVID-19 was addressed.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Drug Delivery Systems[MESH]
  • |*Nanomedicine[MESH]
  • |Animals[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |Clinical Trials as Topic[MESH]
  • |Curcumin/*therapeutic use[MESH]


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