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10.1097/INF.0000000000003081

http://scihub22266oqcxt.onion/10.1097/INF.0000000000003081
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33847299!ä!33847299

suck abstract from ncbi


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pmid33847299      Pediatr+Infect+Dis+J 2021 ; 40 (5): e194-e196
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  • Neonates With SARS-CoV-2 Infection and Pulmonary Disease Safely Treated With Remdesivir #MMPMID33847299
  • Saikia B; Tang J; Robinson S; Nichani S; Lawman KB; Katre M; Bandi S
  • Pediatr Infect Dis J 2021[May]; 40 (5): e194-e196 PMID33847299show ga
  • We describe 2 expremature infants presenting with SARS-CoV-2-related pulmonary disease in their second and fifth week of life needing support with mechanical ventilation. Both infants' initial presentation was with repeated apneas. These cases highlight that SARS-CoV-2 infection could present with apneas and has the potential to progress to more severe pulmonary disease in this high-risk age group of patients. Both patients were treated with remdesivir (RDV). We provide the data of 2 high-risk neonates successfully treated with RDV without observation of any described side effects. A recognition that these high-risk neonates could deteriorate and early multidisciplinary team discussion is the mainstay to the compassionate access to RDV. Our experience led us to develop a guideline on the use of RDV below 12 years of age, with particular focus on infants and young children.
  • |*COVID-19 Drug Treatment[MESH]
  • |Adenosine Monophosphate/adverse effects/*analogs & derivatives/therapeutic use[MESH]
  • |Alanine/adverse effects/*analogs & derivatives/therapeutic use[MESH]
  • |Antiviral Agents/adverse effects/*therapeutic use[MESH]
  • |COVID-19/diagnosis[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Male[MESH]
  • |SARS-CoV-2/isolation & purification[MESH]


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