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Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Brief+Bioinform 2021 ; 22 (5): ä Nephropedia Template TP
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Letter to the Editor: Significant mutation enrichment in inverted repeat sites of new SARS-CoV-2 strains #MMPMID33837760
Bartas M; Goswami P; Lexa M; Cerven J; Volna A; Fojta M; Brazda V; Pecinka P
Brief Bioinform 2021[Sep]; 22 (5): ä PMID33837760show ga
In a recently published paper, we have found that SARS-CoV-2 hot-spot mutations are significantly associated with inverted repeat loci and CG dinucleotides. However, fast-spreading strains with new mutations (so-called mink farm mutations, England mutations and Japan mutations) have been recently described. We used the new datasets to check the positioning of mutation sites in genomes of the new SARS-CoV-2 strains. Using an open-access Palindrome analyzer tool, we found mutations in these new strains to be significantly enriched in inverted repeat loci.