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10.1186/s13643-021-01648-y

http://scihub22266oqcxt.onion/10.1186/s13643-021-01648-y
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33832511!8031340!33832511
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suck abstract from ncbi


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pmid33832511      Syst+Rev 2021 ; 10 (1): 101
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  • The incubation period during the pandemic of COVID-19: a systematic review and meta-analysis #MMPMID33832511
  • Dhouib W; Maatoug J; Ayouni I; Zammit N; Ghammem R; Fredj SB; Ghannem H
  • Syst Rev 2021[Apr]; 10 (1): 101 PMID33832511show ga
  • BACKGROUND: The aim of our study was to determine through a systematic review and meta-analysis the incubation period of COVID-19. It was conducted based on the preferred reporting items for systematic reviews and meta-analyses (PRISMA). Criteria for eligibility were all published population-based primary literature in PubMed interface and the Science Direct, dealing with incubation period of COVID-19, written in English, since December 2019 to December 2020. We estimated the mean of the incubation period using meta-analysis, taking into account between-study heterogeneity, and the analysis with moderator variables. RESULTS: This review included 42 studies done predominantly in China. The mean and median incubation period were of maximum 8 days and 12 days respectively. In various parametric models, the 95th percentiles were in the range 10.3-16 days. The highest 99th percentile would be as long as 20.4 days. Out of the 10 included studies in the meta-analysis, 8 were conducted in China, 1 in Singapore, and 1 in Argentina. The pooled mean incubation period was 6.2 (95% CI 5.4, 7.0) days. The heterogeneity (I(2) 77.1%; p < 0.001) was decreased when we included the study quality and the method of calculation used as moderator variables (I(2) 0%). The mean incubation period ranged from 5.2 (95% CI 4.4 to 5.9) to 6.65 days (95% CI 6.0 to 7.2). CONCLUSIONS: This work provides additional evidence of incubation period for COVID-19 and showed that it is prudent not to dismiss the possibility of incubation periods up to 14 days at this stage of the epidemic.
  • |*COVID-19[MESH]
  • |*Infectious Disease Incubation Period[MESH]
  • |*Pandemics[MESH]
  • |Argentina[MESH]
  • |China[MESH]
  • |Humans[MESH]


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