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10.21101/cejph.a6672

http://scihub22266oqcxt.onion/10.21101/cejph.a6672
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33831279!ä!33831279

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suck abstract from ncbi


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pmid33831279      Cent+Eur+J+Public+Health 2021 ; 29 (1): 3-8
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  • COVID-19 severe pneumonia: Prospective multicentre study on demands on intensive care capacities #MMPMID33831279
  • Dzupova O; Moravec M; Bartos H; Brestovansky P; Tencer T; Hyanek T; Berousek J; Krupkova Z; Mosna F; Vymazal T; Benes J
  • Cent Eur J Public Health 2021[Mar]; 29 (1): 3-8 PMID33831279show ga
  • OBJECTIVES: The aim of the study was to obtain data on demands on the intensive care capacities to treat COVID-19 patients, and to identify predictors for in-hospital mortality. METHODS: The prospective observational multicentre study carried out from 1 March till 30 June 2020 included adult patients with confirmed SARS-CoV-2 infection with respiratory failure requiring ventilatory support or high-flow nasal oxygen therapy (HFNO). RESULTS: Seventy-four patients, 46 males and 28 females, median age 67.5 (Q1-Q3: 56-75) years, were included. Sixty-four patients (86.5%) had comorbidity. Sixty-six patients (89.2%) were mechanically ventilated, four of them received extracorporeal membrane oxygenation therapy. Eight patients (10.8%) were treated with non-invasive ventilation and HFNO only. The median of intensive care unit (ICU) stay was 22.5 days. Eighteen patients (24.3%) needed continuous renal replacement therapy. Thirty patients (40.5%) died. Age and acute kidney injury were identified as independent predictors of in-hospital death, and chronic kidney disease showed trend towards statistical significance for poor outcome. CONCLUSIONS: Sufficient number of intensive care beds, organ support equipment and well-trained staff is a decisive factor in managing the COVID-19 epidemic. The study focused on the needs of intensive care in the COVID-19 patients. Advanced age and acute kidney injury were identified as independent predictors for in-hospital mortality. When compared to clinical course and ICU management of patients with severe community-acquired pneumonia caused by other pathogens, we observed prolonged need for ventilatory support, high rate of progression to acute respiratory distress syndrome and significant mortality in studied population.
  • |*COVID-19[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Critical Care[MESH]
  • |Female[MESH]
  • |Hospital Mortality[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Prospective Studies[MESH]


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