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10.5858/arpa.2020-0851-SA http://scihub22266oqcxt.onion/10.5858/arpa.2020-0851-SA 33821952!ä!33821952 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Arch+Pathol+Lab+Med 2021 ; 145 (8): 929-936 Nephropedia Template TP {{tp|p=33821952|t=2021. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Qualitative Immunoglobulin G Assays: The Value of Numeric Reporting |pdf=|usr=}}{{33821952}} gab.com Text Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Qualitative Immunoglobulin G Assays: The Value of Numeric Reporting JO: Arch Pathol Lab Med http://www.kidney.de/pget.php?&tw=1&pmid=33821952 #FOAvip CONTEXT.-: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) testing is used for serosurveillance and will be important to evaluate vaccination status. Given the urgency to release coronavirus disease 2019 (COVID-19) serology tests, most manufacturers have developed qualitative tests. OBJECTIVE.-: To evaluate clinical performance of 6 different SARS-CoV-2 IgG assays and their quantitative results to better elucidate the clinical role of serology testing in COVID-19. DESIGN.-: Six SARS-CoV-2 IgG assays were tested using remnant specimens from 190 patients. Sensitivity and specificity were evaluated for each assay with the current manufacturer's cutoff and a lower cutoff. A numeric result analysis and discrepancy analysis were performed. RESULTS.-: Specificity was higher than 93% for all assays, and sensitivity was higher than 80% for all assays (>/=7 days post-polymerase chain reaction testing). Inpatients with more severe disease had higher numeric values compared with health care workers with mild or moderate disease. Several discrepant serology results were those just below the manufacturers' cutoff. CONCLUSIONS.-: Severe acute respiratory syndrome coronavirus 2 IgG antibody testing can aid in the diagnosis of COVID-19, especially with negative polymerase chain reaction. Quantitative COVID-19 IgG results are important to better understand the immunologic response and disease course of this novel virus and to assess immunity as part of future vaccination programs. Twit Text FOAVip Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Qualitative Immunoglobulin G Assays: The Value of Numeric Reporting ????Arch Pathol Lab Med http://www.kidney.de/pget.php?&tw=1&pmid=33821952 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33821952 #FOAvip English Wikipedia <ref>{{Cite pmid|33821952}}</ref> Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Qualitative Immunoglobulin G Assays: The Value of Numeric Reporting #MMPMID33821952 Forest SK; Orner EP; Goldstein DY; Wirchnianski AS; Bortz RH; Laudermilch E; Florez C; Malonis RJ; Georgiev GI; Vergnolle O; Lo Y; Campbell ST; Barnhill J; Cadoff EM; Lai JR; Chandran K; Weiss LM; Fox AS; Prystowsky MB; Wolgast LR Arch Pathol Lab Med 2021[Aug]; 145 (8): 929-936 PMID33821952show ga CONTEXT.-: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) testing is used for serosurveillance and will be important to evaluate vaccination status. Given the urgency to release coronavirus disease 2019 (COVID-19) serology tests, most manufacturers have developed qualitative tests. OBJECTIVE.-: To evaluate clinical performance of 6 different SARS-CoV-2 IgG assays and their quantitative results to better elucidate the clinical role of serology testing in COVID-19. DESIGN.-: Six SARS-CoV-2 IgG assays were tested using remnant specimens from 190 patients. Sensitivity and specificity were evaluated for each assay with the current manufacturer's cutoff and a lower cutoff. A numeric result analysis and discrepancy analysis were performed. RESULTS.-: Specificity was higher than 93% for all assays, and sensitivity was higher than 80% for all assays (>/=7 days post-polymerase chain reaction testing). Inpatients with more severe disease had higher numeric values compared with health care workers with mild or moderate disease. Several discrepant serology results were those just below the manufacturers' cutoff. CONCLUSIONS.-: Severe acute respiratory syndrome coronavirus 2 IgG antibody testing can aid in the diagnosis of COVID-19, especially with negative polymerase chain reaction. Quantitative COVID-19 IgG results are important to better understand the immunologic response and disease course of this novel virus and to assess immunity as part of future vaccination programs. |Antibodies, Viral/*blood[MESH] |COVID-19 Nucleic Acid Testing/statistics & numerical data[MESH] |COVID-19 Serological Testing/*methods/statistics & numerical data[MESH] |COVID-19/diagnosis/epidemiology/*immunology[MESH] |Cohort Studies[MESH] |Humans[MESH] |Immunoglobulin G/*blood[MESH] |New York City/epidemiology[MESH] |Pandemics[MESH] |SARS-CoV-2/*immunology[MESH] |Sensitivity and Specificity[MESH]Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Qualitati(epmc).pdf DeepDyve Pubget Overpricing