ECG markers of malignant arrhythmias and in-hospital outcome of COVID-19 pneumonia #MMPMID33821177
Shaghee F; Nafakhi H; Alareedh M; Nafakhi A; Al-Buthabhak K
J Arrhythm 2021[Apr]; 37 (2): 426-431 PMID33821177show ga
BACKGROUND: ECG abnormalities associated with COVID-19 pneumonia and adverse outcome are undefined and poorly described in prior studies. OBJECTIVES: To assess the predictive role of baseline ECG markers of increased risk of malignant arrhythmias and cardiac death for adverse in-hospital outcomes. PATIENTS AND METHODS: A retrospective study included 93 patients of newly diagnosed COVID-19 with features consistent with pneumonia who were admitted to the hospital from August 20 to September 20, 2020. The main outcomes were defined as receiving mechanical ventilation, in-hospital cardiac arrest, length of ICU stay, and degree of lung damage according to computed tomography (CT) score. RESULTS: Increased QTc (QT corrected) interval, Tp-e (T from peak to end) interval, and transmural dispersion of repolarization (TDR) were independent predictors of prolonged ICU stay (P < .0001) after adjustment for baseline clinical characteristics. Increasing age (P < .0001) followed by increased QTc interval (P = .02) and history of chronic lung disease (P = .04) were independent predictors of extensive lung damage. The independent predictors for in-hospital cardiac arrest were increased QTc (P = .02) followed by increasing age (P = .04) and increased Tp-e interval (P = .04). CONCLUSION: Repolarization abnormalities on baseline ECG may be useful prognostic markers in patients with COVID-19 pneumonia.
free
free
free
J+Arrhythm 2021 ; 37 (2): 426-431
