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10.1111/ajco.13570

http://scihub22266oqcxt.onion/10.1111/ajco.13570
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33819387!8251164!33819387
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suck abstract from ncbi


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pmid33819387      Asia+Pac+J+Clin+Oncol 2022 ; 18 (2): e141-e147
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  • Resilience and ongoing quality care for cancer clinical trials during COVID-19: Experience from a tertiary hospital in Australia #MMPMID33819387
  • Ives A; Pusztai T; Keller J; Ahern E; Chan B; Gasper H; Wyld D; Kennedy G; Dickie G; Lwin Z; Roberts NA
  • Asia Pac J Clin Oncol 2022[Apr]; 18 (2): e141-e147 PMID33819387show ga
  • BACKGROUND: The COVID-19 pandemic has forced rapid system-wide changes to be implemented within cancer care at an alarming pace. Clinical trials are a key element of comprehensive cancer care. Ensuring the continuing safe conduct of cancer clinical trials in the context of a pandemic is challenging. METHODS: We aimed to describe the COVID-19 pandemic response of a Cancer Care Clinical Research Unit (CRU) of a tertiary hospital in Queensland, Australia. We used a mixed methods approach for this case study. Emailed directives from CRU managers to all CRU staff sharing were qualitatively analysed and mapped against our unit activities over longitudinal time points. Data from patient recruitment and protocol deviations were analysed using descriptive statistics. RESULTS: Mapping activity from 11 March to 30 September 2020 revealed rapid change during the first 2 weeks. Four key strategies to accommodate change were identified: supporting patients and families, introduction of telehealth, accessing investigational product, and social distancing. Early in the pandemic we recognised that our core key stakeholders were integral to our response. When compared to the previous 12 months, our recruitment numbers dropped markedly in early phases of the response but recovered over time, as we accommodated internal and external impacts. CONCLUSION: Our experience of agility as a necessity, adapting to support patients, and managing both clinical research activity and sponsors during the height of the pandemic response is presented here in order to inform future disaster response planning by clinical trial organisations.
  • |*COVID-19[MESH]
  • |*Neoplasms/therapy[MESH]
  • |Australia/epidemiology[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |SARS-CoV-2[MESH]


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