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10.3389/fpubh.2021.652842 http://scihub22266oqcxt.onion/10.3389/fpubh.2021.652842 33816427!8017277!33816427     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33816427&cmd=llinks): Failed to open stream: HTTP request failed! 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Characteristics of Viral Shedding Time in SARS-CoV-2 Infections: A Systematic Review and Meta-Analysis |pdf=|usr=}}{{33816427}} gab.com Text Characteristics of Viral Shedding Time in SARS-CoV-2 Infections: A Systematic Review and Meta-Analysis JO: Front Public Health http://www.kidney.de/pget.php?&tw=1&pmid=33816427 #FOAvip Background: The viral shedding time (VST) of SARS-CoV-2 mainly determines its transmission and duration of infectiousness. However, it was heterogeneous in the existing studies. Here, we performed a meta-analysis to comprehensively summarize the VST of SARS-CoV-2. Methods: We searched PubMed, Web of Science, MedRxiv, BioRxiv, CNKI, CSTJ, and Wanfang up to October 25, 2020, for studies that reported VSTs of SARS-CoV-2. Pooled estimates and 95% CIs for the VSTs were calculated using log-transformed data. The VSTs in SARS-CoV-2 infections based on different demographic and clinical characteristics, treatments and specimens were stratified by subgroup analysis. Results: A total of 35 studies involving 3,385 participants met the inclusion criteria. The pooled mean VST was 16.8 days (95% CI: 14.8-19.4, I(2) = 99.56%) in SARS-CoV-2 infections. The VST was significantly longer in symptomatic infections (19.7 days, 95% CI: 17.2-22.7, I(2) = 99.34%) than in asymptomatic infections (10.9 days, 95% CI: 8.3-14.3, I(2) = 98.89%) (P < 0.05). The VST was 23.2 days (95% CI: 19.0-28.4, I(2) = 99.24%) in adults, which was significantly longer than that in children (9.9 days, 95% CI: 8.1-12.2, I(2) = 85.74%) (P < 0.05). The VST was significantly longer in persons with chronic diseases (24.2 days, 95% CI: 19.2-30.2, I(2) = 84.07%) than in those without chronic diseases (11.5 days, 95% CI: 5.3-25.0, I(2) = 82.11%) (P < 0.05). Persons receiving corticosteroid treatment (28.3 days, 95% CI: 25.6-31.2, I(2) = 0.00%) had a longer VST than those without corticosteroid treatment (16.2 days, 95% CI: 11.5-22.5, I(2) = 92.27%) (P = 0.06). The VST was significantly longer in stool specimens (30.3 days, 95% CI: 23.1-39.2, I(2) = 92.09%) than in respiratory tract specimens (17.5 days, 95% CI: 14.9-20.6, I(2) = 99.67%) (P < 0.05). Conclusions: A longer VST was found in symptomatic infections, infected adults, persons with chronic diseases, and stool specimens. Twit Text FOAVip Characteristics of Viral Shedding Time in SARS-CoV-2 Infections: A Systematic Review and Meta-Analysis ????Front Public Health http://www.kidney.de/pget.php?&tw=1&pmid=33816427 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33816427 #FOAvip English Wikipedia <ref>{{Cite pmid|33816427}}</ref> Characteristics of Viral Shedding Time in SARS-CoV-2 Infections: A Systematic Review and Meta-Analysis #MMPMID33816427 Yan D; Zhang X; Chen C; Jiang D; Liu X; Zhou Y; Huang C; Zhou Y; Guan Z; Ding C; Chen L; Lan L; Fu X; Wu J; Li L; Yang S Front Public Health 2021[]; 9 (ä): 652842 PMID33816427show ga Background: The viral shedding time (VST) of SARS-CoV-2 mainly determines its transmission and duration of infectiousness. However, it was heterogeneous in the existing studies. Here, we performed a meta-analysis to comprehensively summarize the VST of SARS-CoV-2. Methods: We searched PubMed, Web of Science, MedRxiv, BioRxiv, CNKI, CSTJ, and Wanfang up to October 25, 2020, for studies that reported VSTs of SARS-CoV-2. Pooled estimates and 95% CIs for the VSTs were calculated using log-transformed data. The VSTs in SARS-CoV-2 infections based on different demographic and clinical characteristics, treatments and specimens were stratified by subgroup analysis. Results: A total of 35 studies involving 3,385 participants met the inclusion criteria. The pooled mean VST was 16.8 days (95% CI: 14.8-19.4, I(2) = 99.56%) in SARS-CoV-2 infections. The VST was significantly longer in symptomatic infections (19.7 days, 95% CI: 17.2-22.7, I(2) = 99.34%) than in asymptomatic infections (10.9 days, 95% CI: 8.3-14.3, I(2) = 98.89%) (P < 0.05). The VST was 23.2 days (95% CI: 19.0-28.4, I(2) = 99.24%) in adults, which was significantly longer than that in children (9.9 days, 95% CI: 8.1-12.2, I(2) = 85.74%) (P < 0.05). The VST was significantly longer in persons with chronic diseases (24.2 days, 95% CI: 19.2-30.2, I(2) = 84.07%) than in those without chronic diseases (11.5 days, 95% CI: 5.3-25.0, I(2) = 82.11%) (P < 0.05). Persons receiving corticosteroid treatment (28.3 days, 95% CI: 25.6-31.2, I(2) = 0.00%) had a longer VST than those without corticosteroid treatment (16.2 days, 95% CI: 11.5-22.5, I(2) = 92.27%) (P = 0.06). The VST was significantly longer in stool specimens (30.3 days, 95% CI: 23.1-39.2, I(2) = 92.09%) than in respiratory tract specimens (17.5 days, 95% CI: 14.9-20.6, I(2) = 99.67%) (P < 0.05). Conclusions: A longer VST was found in symptomatic infections, infected adults, persons with chronic diseases, and stool specimens. |*Virus Shedding[MESH] |Adrenal Cortex Hormones/therapeutic use[MESH] |Adult[MESH] |Asymptomatic Infections[MESH] |COVID-19/*virology[MESH] |Child[MESH] |Comorbidity[MESH] |Feces/virology[MESH] |Humans[MESH]Characteristics of Viral Shedding Time in SARS-CoV-2 Infections: A Sys(epmc).pdf DeepDyve Pubget Overpricing