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10.5501/wjv.v10.i2.34 http://scihub22266oqcxt.onion/10.5501/wjv.v10.i2.34 33816149!7995409!33816149     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       World+J+Virol 2021 ; 10 (2): 34-52 Nephropedia Template TP {{tp|p=33816149|t=2021. Bottom-up analysis of emergent properties of N-acetylcysteine as an adjuvant therapy for COVID-19 |pdf=|usr=}}{{33816149}} gab.com Text Bottom-up analysis of emergent properties of N-acetylcysteine as an adjuvant therapy for COVID-19 JO: World J Virol http://www.kidney.de/pget.php?&tw=1&pmid=33816149 #FOAvip N-acetylcysteine (NAC) is an abundantly available antioxidant with a wide range of antidotal properties currently best studied for its use in treating acetaminophen overdose. It has a robustly established safety profile with easily tolerated side effects and presents the Food and Drug Administration's approval for use in treating acetaminophen overdose patients. It has been proven efficacious in off-label uses, such as in respiratory diseases, heart disease, cancer, human immunodeficiency virus infection, and seasonal influenza. Clinical trials have recently shown that NAC's capacity to replenish glutathione stores may significantly improve coronavirus disease 2019 (COVID-19) outcomes, especially in high risk individuals. Interestingly, individuals with glucose 6-phosphate dehydrogenase deficiency have been shown to experience even greater benefit. The same study has concluded that NAC's ability to mitigate the impact of the cytokine storm and prevent elevation of liver enzymes, C-reactive protein, and ferritin is associated with higher success rates weaning from the ventilator and return to normal function in COVID-19 patients. Considering the background knowledge of biochemistry, current uses of NAC in clinical practice, and newly acquired evidence on its potential efficacy against COVID-19, it is worthwhile to investigate further whether this agent can be used as a treatment or adjuvant for COVID-19. Twit Text FOAVip Bottom-up analysis of emergent properties of N-acetylcysteine as an adjuvant therapy for COVID-19 ????World J Virol http://www.kidney.de/pget.php?&tw=1&pmid=33816149 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33816149 #FOAvip English Wikipedia <ref>{{Cite pmid|33816149}}</ref> Bottom-up analysis of emergent properties of N-acetylcysteine as an adjuvant therapy for COVID-19 #MMPMID33816149 Dominari A; Hathaway Iii D; Kapasi A; Paul T; Makkar SS; Castaneda V; Gara S; Singh BM; Agadi K; Butt M; Retnakumar V; Chittajallu S; Taugir R; Sana MK; Kc M; Razzack S; Moallem N; Alvarez A; Talalaev M World J Virol 2021[Mar]; 10 (2): 34-52 PMID33816149show ga N-acetylcysteine (NAC) is an abundantly available antioxidant with a wide range of antidotal properties currently best studied for its use in treating acetaminophen overdose. It has a robustly established safety profile with easily tolerated side effects and presents the Food and Drug Administration's approval for use in treating acetaminophen overdose patients. It has been proven efficacious in off-label uses, such as in respiratory diseases, heart disease, cancer, human immunodeficiency virus infection, and seasonal influenza. Clinical trials have recently shown that NAC's capacity to replenish glutathione stores may significantly improve coronavirus disease 2019 (COVID-19) outcomes, especially in high risk individuals. Interestingly, individuals with glucose 6-phosphate dehydrogenase deficiency have been shown to experience even greater benefit. The same study has concluded that NAC's ability to mitigate the impact of the cytokine storm and prevent elevation of liver enzymes, C-reactive protein, and ferritin is associated with higher success rates weaning from the ventilator and return to normal function in COVID-19 patients. Considering the background knowledge of biochemistry, current uses of NAC in clinical practice, and newly acquired evidence on its potential efficacy against COVID-19, it is worthwhile to investigate further whether this agent can be used as a treatment or adjuvant for COVID-19. äBottom-up analysis of emergent properties of N-acetylcysteine as an ad(epmc).pdf DeepDyve Pubget Overpricing