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10.1016/j.jtumed.2021.03.001

http://scihub22266oqcxt.onion/10.1016/j.jtumed.2021.03.001
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33815034!8007413!33815034
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suck abstract from ncbi


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pmid33815034      J+Taibah+Univ+Med+Sci 2021 ; 16 (4): 612-618
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  • The willingness of the Saudi Arabian population to participate in the COVID-19 vaccine trial: A case-control study #MMPMID33815034
  • Felemban RM; Tashkandi EM; Mohorjy DK
  • J Taibah Univ Med Sci 2021[Aug]; 16 (4): 612-618 PMID33815034show ga
  • OBJECTIVES: This study examines the Saudi Arabian population's willingness to participate in clinical trials for the coronavirus disease 2019 (COVID-19) vaccine, comparing recovered cases' willingness with that of healthy volunteers. METHODS: A case-control study was conducted on the Saudi Arabian population during September 2020. The data were collected from recovered COVID-19 participants as the case group, and healthy volunteers as the control group. RESULTS: The data showed that 42.2% (n = 315) of recovered COVID-19 cases were more willing to participate in the COVID-19 vaccine trial than healthy volunteers (299; 38.1%) with a p < 0.001. The proportion of the participants who were willing to donate plasma was significantly higher among recovered participants, 84.2% (n = 112), than healthy volunteers, 76.3% (n = 87), with a p < 0.0001. The most significant factor responsible for a willingness to participate was the belief that vaccine discovery would help scientific developments (r = 0.525 and 0.465 for case and control, respectively). In comparison, significant reasons behind the unwillingness to participate were the risk of exposure to an unproven vaccine, r = 0.377 and 0.497 for case and control, respectively (p < 0.001), and a discomfort with being treated as an experimental subject (r = 0.275 and 0.374 for case and control, respectively). CONCLUSIONS: The differences in readiness toward the COVID-19 vaccine trial in our study does not indicate any passive exposure of participants to an unproven clinical trial vaccine, nor does it shed light on well-informed risk-related decisions. However, certain factors can significantly influence decision-making while contributing toward clinical research. This study's results must not be used for the individuals' recruitment bias in a COVID-19 vaccine trial.
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