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10.3390/pathogens10030380

http://scihub22266oqcxt.onion/10.3390/pathogens10030380
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33809954!8004127!33809954
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suck abstract from ncbi


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pmid33809954      Pathogens 2021 ; 10 (3): ä
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  • Why Does SARS-CoV-2 Infection Induce Autoantibody Production? #MMPMID33809954
  • Macela A; Kubelkova K
  • Pathogens 2021[Mar]; 10 (3): ä PMID33809954show ga
  • SARS-CoV-2 infection induces the production of autoantibodies, which is significantly associated with complications during hospitalization and a more severe prognosis in COVID-19 patients. Such a response of the patient's immune system may reflect (1) the dysregulation of the immune response or (2) it may be an attempt to regulate itself in situations where the non-infectious self poses a greater threat than the infectious non-self. Of significance may be the primary virus-host cell interaction where the surface-bound ACE2 ectoenzyme plays a critical role. Here, we present a brief analysis of recent findings concerning the immune recognition of SARS-CoV-2, which, we believe, favors the second possibility as the underlying reason for the production of autoantibodies during COVID-19.
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