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10.1016/j.cbi.2021.109449 http://scihub22266oqcxt.onion/10.1016/j.cbi.2021.109449 33798507!8008820!33798507     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Chem+Biol+Interact 2021 ; 341 (ä): 109449 Nephropedia Template TP {{tp|p=33798507|t=2021. Role of phytoconstituents in the management of COVID-19 |pdf=|usr=}}{{33798507}} gab.com Text Role of phytoconstituents in the management of COVID-19 JO: Chem Biol Interact http://www.kidney.de/pget.php?&tw=1&pmid=33798507 #FOAvip BACKGROUND: COVID-19, a severe global pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has emerged as one of the most threatening transmissible disease. As a great threat to global public health, the development of treatment options has become vital, and a rush to find a cure has mobilized researchers globally from all areas. SCOPE AND APPROACH: This review focuses on deciphering the potential of different secondary metabolites from medicinal plants as therapeutic options either as inhibitors of therapeutic targets of SARS-CoV-2 or as blockers of viral particles entry through host cell receptors. The use of medicinal plants containing specific phytomoieties could be seen in providing a safer and long-term solution for the population with lesser side effects. Key Findings and Conclusions: Considering the high cost and time-consuming drug discovery process, therapeutic repositioning of existing drugs was explored as treatment option in COVID-19, however several molecules have been retracted as therapeutics either due to no positive outcomes or the severe side effects. These effects call for exploring the alternate treatment options which are therapeutically effective as well as safe. Keeping this in mind, phytopharmaceuticals derived from medicinal plants could be explored as important resources in the development of COVID-19 treatment, as their role in the past for treatment of viral diseases like HIV, MERS-CoV, and influenza has been well reported. Considering this fact, different phytoconstituents such as flavonoids, alkaloids, tannins and glycosides etc. Possessing antiviral properties against coronaviruses and possessing potential against SARS-CoV-2 have been reviewed in the present work. Twit Text FOAVip Role of phytoconstituents in the management of COVID-19 ????Chem Biol Interact http://www.kidney.de/pget.php?&tw=1&pmid=33798507 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33798507 #FOAvip English Wikipedia <ref>{{Cite pmid|33798507}}</ref> Role of phytoconstituents in the management of COVID-19 #MMPMID33798507 Das A; Pandita D; Jain GK; Agarwal P; Grewal AS; Khar RK; Lather V Chem Biol Interact 2021[May]; 341 (ä): 109449 PMID33798507show ga BACKGROUND: COVID-19, a severe global pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has emerged as one of the most threatening transmissible disease. As a great threat to global public health, the development of treatment options has become vital, and a rush to find a cure has mobilized researchers globally from all areas. SCOPE AND APPROACH: This review focuses on deciphering the potential of different secondary metabolites from medicinal plants as therapeutic options either as inhibitors of therapeutic targets of SARS-CoV-2 or as blockers of viral particles entry through host cell receptors. The use of medicinal plants containing specific phytomoieties could be seen in providing a safer and long-term solution for the population with lesser side effects. Key Findings and Conclusions: Considering the high cost and time-consuming drug discovery process, therapeutic repositioning of existing drugs was explored as treatment option in COVID-19, however several molecules have been retracted as therapeutics either due to no positive outcomes or the severe side effects. These effects call for exploring the alternate treatment options which are therapeutically effective as well as safe. Keeping this in mind, phytopharmaceuticals derived from medicinal plants could be explored as important resources in the development of COVID-19 treatment, as their role in the past for treatment of viral diseases like HIV, MERS-CoV, and influenza has been well reported. Considering this fact, different phytoconstituents such as flavonoids, alkaloids, tannins and glycosides etc. Possessing antiviral properties against coronaviruses and possessing potential against SARS-CoV-2 have been reviewed in the present work. |*COVID-19 Drug Treatment[MESH] |Alkaloids/chemistry/pharmacology[MESH] |Anthraquinones/chemistry/pharmacology[MESH] |Antiviral Agents/chemistry/*pharmacology[MESH] |Flavonoids/chemistry/pharmacology[MESH] |Humans[MESH] |Oils, Volatile/chemistry/pharmacology[MESH] |Phytochemicals/chemistry/*pharmacology[MESH] |Plants, Medicinal/chemistry/metabolism[MESH] |Saponins/chemistry/pharmacology[MESH]Role of phytoconstituents in the management of COVID-19 (epmc).pdf DeepDyve Pubget Overpricing