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10.1016/j.chom.2021.03.009 http://scihub22266oqcxt.onion/10.1016/j.chom.2021.03.009 33798491!7980225!33798491     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Host+Microbe 2021 ; 29 (4): 516-521.e3 Nephropedia Template TP {{tp|p=33798491|t=2021. Infection- and vaccine-induced antibody binding and neutralization of the B 1 351 SARS-CoV-2 variant |pdf=|usr=}}{{33798491}} gab.com Text Infection- and vaccine-induced antibody binding and neutralization of the B 1 351 SARS-CoV-2 variant JO: Cell Host Microbe http://www.kidney.de/pget.php?&tw=1&pmid=33798491 #FOAvip The emergence of SARS-CoV-2 variants with mutations in the spike protein is raising concerns about the efficacy of infection- or vaccine-induced antibodies. We compared antibody binding and live virus neutralization of sera from naturally infected and Moderna-vaccinated individuals against two SARS-CoV-2 variants: B.1 containing the spike mutation D614G and the emerging B.1.351 variant containing additional spike mutations and deletions. Sera from acutely infected and convalescent COVID-19 patients exhibited a 3-fold reduction in binding antibody titers to the B.1.351 variant receptor-binding domain of the spike protein and a 3.5-fold reduction in neutralizing antibody titers against SARS-CoV-2 B.1.351 variant compared to the B.1 variant. Similar results were seen with sera from Moderna-vaccinated individuals. Despite reduced antibody titers against the B.1.351 variant, sera from infected and vaccinated individuals containing polyclonal antibodies to the spike protein could still neutralize SARS-CoV-2 B.1.351, suggesting that protective humoral immunity may be retained against this variant. Twit Text FOAVip Infection- and vaccine-induced antibody binding and neutralization of the B 1 351 SARS-CoV-2 variant ????Cell Host Microbe http://www.kidney.de/pget.php?&tw=1&pmid=33798491 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33798491 #FOAvip English Wikipedia <ref>{{Cite pmid|33798491}}</ref> Infection- and vaccine-induced antibody binding and neutralization of the B 1 351 SARS-CoV-2 variant #MMPMID33798491 Edara VV; Norwood C; Floyd K; Lai L; Davis-Gardner ME; Hudson WH; Mantus G; Nyhoff LE; Adelman MW; Fineman R; Patel S; Byram R; Gomes DN; Michael G; Abdullahi H; Beydoun N; Panganiban B; McNair N; Hellmeister K; Pitts J; Winters J; Kleinhenz J; Usher J; O'Keefe JB; Piantadosi A; Waggoner JJ; Babiker A; Stephens DS; Anderson EJ; Edupuganti S; Rouphael N; Ahmed R; Wrammert J; Suthar MS Cell Host Microbe 2021[Apr]; 29 (4): 516-521.e3 PMID33798491show ga The emergence of SARS-CoV-2 variants with mutations in the spike protein is raising concerns about the efficacy of infection- or vaccine-induced antibodies. We compared antibody binding and live virus neutralization of sera from naturally infected and Moderna-vaccinated individuals against two SARS-CoV-2 variants: B.1 containing the spike mutation D614G and the emerging B.1.351 variant containing additional spike mutations and deletions. Sera from acutely infected and convalescent COVID-19 patients exhibited a 3-fold reduction in binding antibody titers to the B.1.351 variant receptor-binding domain of the spike protein and a 3.5-fold reduction in neutralizing antibody titers against SARS-CoV-2 B.1.351 variant compared to the B.1 variant. Similar results were seen with sera from Moderna-vaccinated individuals. Despite reduced antibody titers against the B.1.351 variant, sera from infected and vaccinated individuals containing polyclonal antibodies to the spike protein could still neutralize SARS-CoV-2 B.1.351, suggesting that protective humoral immunity may be retained against this variant. |Antibodies, Neutralizing/*immunology[MESH] |Antibodies, Viral/*immunology[MESH] |Binding Sites[MESH] |COVID-19 Vaccines/*immunology[MESH] |COVID-19/*immunology/prevention & control[MESH] |Humans[MESH] |Neutralization Tests[MESH] |Receptors, Virus/chemistry[MESH]Infection- and vaccine-induced antibody binding and neutralization of (epmc).pdf DeepDyve Pubget Overpricing