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10.1165/rcmb.2020-0236TR http://scihub22266oqcxt.onion/10.1165/rcmb.2020-0236TR 33797351!8320126!33797351     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Respir+Cell+Mol+Biol 2021 ; 65 (1): 13-21 Nephropedia Template TP {{tp|p=33797351|t=2021. The Role of Obesity in the Immunopathogenesis of COVID-19 Respiratory Disease and Critical Illness |pdf=|usr=}}{{33797351}} gab.com Text The Role of Obesity in the Immunopathogenesis of COVID-19 Respiratory Disease and Critical Illness JO: Am J Respir Cell Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=33797351 #FOAvip Coronavirus disease (COVID-19), the clinical syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently a global health pandemic with substantial morbidity and mortality. COVID-19 has cast a shadow on nearly every aspect of society, straining health systems and economies across the world. Although it is widely accepted that a close relationship exists between obesity, cardiovascular disease, and metabolic disorders on infection, we are only beginning to understand ways in which the immunological sequelae of obesity functions as a predisposing factor related to poor clinical outcomes in COVID-19. As both the innate and adaptive immune systems are each primed by obesity, the alteration of key pathways results in both an immunosuppressed and hyperinflammatory state. The present review will discuss the cellular and molecular immunology of obesity in the context of its role as a risk factor for severe COVID-19, discuss the role of cytokine storm, and draw parallels to prior viral epidemics such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and 2009 H1N1. Twit Text FOAVip The Role of Obesity in the Immunopathogenesis of COVID-19 Respiratory Disease and Critical Illness ????Am J Respir Cell Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=33797351 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33797351 #FOAvip English Wikipedia <ref>{{Cite pmid|33797351}}</ref> The Role of Obesity in the Immunopathogenesis of COVID-19 Respiratory Disease and Critical Illness #MMPMID33797351 Kuperberg SJ; Navetta-Modrov B Am J Respir Cell Mol Biol 2021[Jul]; 65 (1): 13-21 PMID33797351show ga Coronavirus disease (COVID-19), the clinical syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently a global health pandemic with substantial morbidity and mortality. COVID-19 has cast a shadow on nearly every aspect of society, straining health systems and economies across the world. Although it is widely accepted that a close relationship exists between obesity, cardiovascular disease, and metabolic disorders on infection, we are only beginning to understand ways in which the immunological sequelae of obesity functions as a predisposing factor related to poor clinical outcomes in COVID-19. As both the innate and adaptive immune systems are each primed by obesity, the alteration of key pathways results in both an immunosuppressed and hyperinflammatory state. The present review will discuss the cellular and molecular immunology of obesity in the context of its role as a risk factor for severe COVID-19, discuss the role of cytokine storm, and draw parallels to prior viral epidemics such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and 2009 H1N1. |*COVID-19/immunology/metabolism/mortality[MESH] |*Cardiovascular Diseases/immunology/metabolism/mortality[MESH] |*Cytokine Release Syndrome/immunology/metabolism/mortality/virology[MESH] |*Obesity/immunology/metabolism/mortality/virology[MESH] |*SARS-CoV-2/immunology/metabolism[MESH] |Critical Illness[MESH] |Disease-Free Survival[MESH] |Humans[MESH]The Role of Obesity in the Immunopathogenesis of COVID-19 Respiratory (epmc).pdf DeepDyve Pubget Overpricing