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10.1177/2040620720983127 http://scihub22266oqcxt.onion/10.1177/2040620720983127 33796233!7970675!33796233     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33796233&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Ther+Adv+Hematol 2021 ; 12 (?): 2040620720983127 Nephropedia Template TP {{tp|p=33796233|t=2021. Clinicopathological characteristics and long-term prognosis of monoclonal immunoglobulin light chain associated Fanconi syndrome |pdf=|usr=}}{{33796233}} gab.com Text Clinicopathological characteristics and long-term prognosis of monoclonal immunoglobulin light chain associated Fanconi syndrome JO: Ther Adv Hematol http://www.kidney.de/pget.php?&tw=1&pmid=33796233 #FOAvip BACKGROUND AND AIMS: Monoclonal immunoglobulin light chain associated Fanconi syndrome (LC-FS) is a rare disease that involves proximal tubules. As most of the reported cases came from western countries, we aimed to analyze the clinicopathological characteristics of Asian LC-FS and its treatment responses to chemotherapy. METHODS: A total of 26 LC-FS patients in a single-center were retrospectively studied. RESULTS: At diagnosis, the mean age of the 26 Asian LC-FS patients was 54.7 +/- 14.7 years, with females accounting for 57.7%. They presented with different degrees of proximal tubular dysfunctions with normoglycemic glycosuria (88.0%), hyperphosphaturia (84.2%) and aminoaciduria (84.0%) as the most common features. The mean estimated glomerular filtration rate (eGFR) was (68.0 +/- 26.4) ml/min per 1.73 m(2). After chemotherapy, renal response was achieved in 58.3% cases, which was accompanied by hematological response, and tubular response was acquired in 66.7% cases. During 3 years of follow-up, the eGFR levels significantly decreased in the monoclonal gammopathy of renal significance patients, few of whom (21.4%) had received chemotherapy. CONCLUSION: Asian LC-FS patients had mild renal function disorder. The chemotherapy could improve both renal and tubular functions, which may be related to the hematological response. Twit Text FOAVip Clinicopathological characteristics and long-term prognosis of monoclonal immunoglobulin light chain associated Fanconi syndrome ????Ther Adv Hematol http://www.kidney.de/pget.php?&tw=1&pmid=33796233 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33796233 #FOAvip English Wikipedia <ref>{{Cite pmid|33796233}}</ref> Clinicopathological characteristics and long-term prognosis of monoclonal immunoglobulin light chain associated Fanconi syndrome #MMPMID33796233 Chen Z; Li J; Shi X; Wang Y; Xia P; Ye W; Ye W; Qin Y; Li H; Li M; Li X; Wen Y; Chen L Ther Adv Hematol 2021[]; 12 (?): 2040620720983127 PMID33796233show ga BACKGROUND AND AIMS: Monoclonal immunoglobulin light chain associated Fanconi syndrome (LC-FS) is a rare disease that involves proximal tubules. As most of the reported cases came from western countries, we aimed to analyze the clinicopathological characteristics of Asian LC-FS and its treatment responses to chemotherapy. METHODS: A total of 26 LC-FS patients in a single-center were retrospectively studied. RESULTS: At diagnosis, the mean age of the 26 Asian LC-FS patients was 54.7 +/- 14.7 years, with females accounting for 57.7%. They presented with different degrees of proximal tubular dysfunctions with normoglycemic glycosuria (88.0%), hyperphosphaturia (84.2%) and aminoaciduria (84.0%) as the most common features. The mean estimated glomerular filtration rate (eGFR) was (68.0 +/- 26.4) ml/min per 1.73 m(2). After chemotherapy, renal response was achieved in 58.3% cases, which was accompanied by hematological response, and tubular response was acquired in 66.7% cases. During 3 years of follow-up, the eGFR levels significantly decreased in the monoclonal gammopathy of renal significance patients, few of whom (21.4%) had received chemotherapy. CONCLUSION: Asian LC-FS patients had mild renal function disorder. The chemotherapy could improve both renal and tubular functions, which may be related to the hematological response. ?Clinicopathological characteristics and long-term prognosis of monoclo(epmc).pdf DeepDyve Pubget Overpricing