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10.1002/rmv.2236 http://scihub22266oqcxt.onion/10.1002/rmv.2236 33793006!8250062!33793006     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Rev+Med+Virol 2021 ; 31 (6): e2236 Nephropedia Template TP {{tp|p=33793006|t=2021. Features of HLA class I expression and its clinical relevance in SARS-CoV-2: What do we know so far?|pdf=|usr=}}{{33793006}} gab.com Text Features of HLA class I expression and its clinical relevance in SARS-CoV-2: What do we know so far JO: Rev Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=33793006 #FOAvip Modifications in HLA-I expression are found in many viral diseases. They represent one of the immune evasion strategies most widely used by viruses to block antigen presentation and NK cell response, and SARS-CoV-2 is no exception. These alterations result from a combination of virus-specific factors, genetically encoded mechanisms, and the status of host defences and range from loss or upregulation of HLA-I molecules to selective increases of HLA-I alleles. In this review, I will first analyse characteristic features of altered HLA-I expression found in SARS-CoV-2. I will then discuss the potential factors underlying these defects, focussing on HLA-E and class-I-related (like) molecules and their receptors, the most documented HLA-I alterations. I will also draw attention to potential differences between cells transfected to express viral proteins and those presented as part of authentic infection. Consideration of these factors and others affecting HLA-I expression may provide us with improved possibilities for research into cellular immunity against viral variants. Twit Text FOAVip Features of HLA class I expression and its clinical relevance in SARS-CoV-2: What do we know so far ????Rev Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=33793006 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33793006 #FOAvip English Wikipedia <ref>{{Cite pmid|33793006}}</ref> Features of HLA class I expression and its clinical relevance in SARS-CoV-2: What do we know so far? #MMPMID33793006 Bouayad A Rev Med Virol 2021[Nov]; 31 (6): e2236 PMID33793006show ga Modifications in HLA-I expression are found in many viral diseases. They represent one of the immune evasion strategies most widely used by viruses to block antigen presentation and NK cell response, and SARS-CoV-2 is no exception. These alterations result from a combination of virus-specific factors, genetically encoded mechanisms, and the status of host defences and range from loss or upregulation of HLA-I molecules to selective increases of HLA-I alleles. In this review, I will first analyse characteristic features of altered HLA-I expression found in SARS-CoV-2. I will then discuss the potential factors underlying these defects, focussing on HLA-E and class-I-related (like) molecules and their receptors, the most documented HLA-I alterations. I will also draw attention to potential differences between cells transfected to express viral proteins and those presented as part of authentic infection. Consideration of these factors and others affecting HLA-I expression may provide us with improved possibilities for research into cellular immunity against viral variants. |*Antigenic Variation[MESH] |*Clonal Anergy[MESH] |*Immune Evasion[MESH] |Alleles[MESH] |COVID-19/*immunology/pathology/virology[MESH] |Cytokines/genetics/immunology[MESH] |Cytotoxicity, Immunologic[MESH] |Gene Expression[MESH] |Histocompatibility Antigens Class I/genetics/*immunology[MESH] |Humans[MESH] |Immunity, Cellular[MESH] |Killer Cells, Natural/immunology/virology[MESH] |NK Cell Lectin-Like Receptor Subfamily C/genetics/immunology[MESH] |NK Cell Lectin-Like Receptor Subfamily D/genetics/immunology[MESH] |SARS-CoV-2/*genetics/immunology/pathogenicity[MESH]Features of HLA class I expression and its clinical relevance in SARS-(epmc).pdf DeepDyve Pubget Overpricing