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10.1002/cpt.2248 http://scihub22266oqcxt.onion/10.1002/cpt.2248 33792920!ä!33792920 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Pharmacol+Ther 2022 ; 111 (2): 373-381 Nephropedia Template TP {{tp|p=33792920|t=2022. Perspectives on Virtual (Remote) Clinical Trials as the "New Normal" to Accelerate Drug Development |pdf=|usr=}}{{33792920}} gab.com Text Perspectives on Virtual (Remote) Clinical Trials as the "New Normal" to Accelerate Drug Development JO: Clin Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=33792920 #FOAvip Although the digital revolution has transformed many areas of human endeavor, pharmaceutical drug development has been relatively slow to embrace the emerging technologies to enhance efficiency and optimize value in clinical trials. The topic has garnered even greater attention in the face of the coronavirus disease 2019 (COVID-19) outbreak, which has caused unprecedented disruption in the conduct of clinical trials and presented considerable challenges and opportunities for clinical trialists and data analysts. In this paper, we highlight the potential opportunity with virtual or digital clinical trials as viable options to enhance efficiency in drug development and, more importantly, in offering diverse patients easier and attractive means to participate in clinical trials. Special reference is made to the implication of artificial intelligence and machine-learning tools in trial execution and data acquisition, processing, and analysis in a virtual trial setting. Issues of patient safety, measurement validity, and data integrity are reviewed, and considerations are put forth with reference to the mitigation of underlying regulatory and operational barriers. Twit Text FOAVip Perspectives on Virtual (Remote) Clinical Trials as the "New Normal" to Accelerate Drug Development ????Clin Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=33792920 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33792920 #FOAvip English Wikipedia <ref>{{Cite pmid|33792920}}</ref> Perspectives on Virtual (Remote) Clinical Trials as the "New Normal" to Accelerate Drug Development #MMPMID33792920 Alemayehu D; Hemmings R; Natarajan K; Roychoudhury S Clin Pharmacol Ther 2022[Feb]; 111 (2): 373-381 PMID33792920show ga Although the digital revolution has transformed many areas of human endeavor, pharmaceutical drug development has been relatively slow to embrace the emerging technologies to enhance efficiency and optimize value in clinical trials. The topic has garnered even greater attention in the face of the coronavirus disease 2019 (COVID-19) outbreak, which has caused unprecedented disruption in the conduct of clinical trials and presented considerable challenges and opportunities for clinical trialists and data analysts. In this paper, we highlight the potential opportunity with virtual or digital clinical trials as viable options to enhance efficiency in drug development and, more importantly, in offering diverse patients easier and attractive means to participate in clinical trials. Special reference is made to the implication of artificial intelligence and machine-learning tools in trial execution and data acquisition, processing, and analysis in a virtual trial setting. Issues of patient safety, measurement validity, and data integrity are reviewed, and considerations are put forth with reference to the mitigation of underlying regulatory and operational barriers. |*Virtual Reality[MESH] |Artificial Intelligence[MESH] |COVID-19/*epidemiology[MESH] |Drug Development/*organization & administration[MESH] |Electronic Data Processing[MESH] |Humans[MESH] |Pandemics[MESH] |Randomized Controlled Trials as Topic/*methods[MESH] |SARS-CoV-2[MESH] |Telemedicine/*organization & administration[MESH]Perspectives on Virtual (Remote) Clinical Trials as the "New Normal" t(epmc).pdf DeepDyve Pubget Overpricing