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10.1007/s00431-021-04052-9 http://scihub22266oqcxt.onion/10.1007/s00431-021-04052-9 33791862!8012155!33791862     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33791862&cmd=llinks): Failed to open stream: HTTP request failed! 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Pediatric multisystem SARS COV2 with versus without cardiac involvement: a multicenter study from Latin America |pdf=|usr=}}{{33791862}} gab.com Text Pediatric multisystem SARS COV2 with versus without cardiac involvement: a multicenter study from Latin America JO: Eur J Pediatr http://www.kidney.de/pget.php?&tw=1&pmid=33791862 #FOAvip Latin America (LATAM) children offer special insight into Severe Acute Respiratory Syndrome Coronavirus 2 (SARS COV2) due to high-risk race/ethnicity, variability in medical resources, diverse socioeconomic background, and numerous involved organ systems. This multinational study of LATAM youth examined the distinguishing features of acute or late multisystem SARS COV2 with versus without cardiac involvement. A consecutive sample of youth 0-18 years old (N = 98;50% male) presenting with multisystem SARS COV2 to 32 centers in 10 Latin American countries participating in a pediatric cardiac multi-imaging society were grouped as with versus without cardiac involvement, defined as abnormal echocardiographic findings or arrhythmia. Collected clinical data were analyzed by Student's t-test or Fisher's exact test. Cardiac (N = 48, 50% male) versus no cardiac (N = 50, 50% male) were similar in age; weight; nonrespiratory symptoms; and medical history. The cardiac group had 1 death and symptoms including coronary artery dilation, ejection fraction <50%, pericardial effusion, peripheral edema, arrhythmia, and pulmonary artery thrombus. The cardiac group had higher risk of ICU admission (77% vs 54%, p = 0.02); invasive ventilation (23% vs 4%,p = 0.007); vasoactive infusions (27% vs 4%, p = 0.002); prominent respiratory symptoms (60% vs 36%, p < 0.03); abnormal chest imaging (69% vs 34%, p = 0.001); troponin (33% vs 12%, p = 0.01); alanine aminotransferase (33% vs 12%, p = 0.02); and thrombocytopenia (46% vs 22%, p = 0.02). Receiver operating curve analysis showed that abnormal laboratories had 94% sensitivity and 98% negative predictive value on the need for ICU interventions.Conclusion: In LATAM children with multisystem SARS COV2, cardiac involvement was prevalent. Cardiac involvement was more likely to require ICU interventions, certain abnormal labs, and respiratory involvement. What is Known: * SARS COV2 can be asymptomatic in children but in some cases can have serious multisystemic involvement. * Hispanic ethnicity is purportedly at high risk of SARS COV2 in nations where they are often disadvantaged minority populations. What is New: * Latin American children presenting with multisystem SARS COV2 frequently have cardiac involvement which was associated with ICU interventions; prominent respiratory symptoms; abnormal chest X-ray; elevated troponin, ALT, and thrombocytopenia. * Elevated troponin, ALT or thrombocytopenia had high sensitivity and negative predictive value on the need for intensive care interventions. Twit Text FOAVip Pediatric multisystem SARS COV2 with versus without cardiac involvement: a multicenter study from Latin America ????Eur J Pediatr http://www.kidney.de/pget.php?&tw=1&pmid=33791862 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33791862 #FOAvip English Wikipedia <ref>{{Cite pmid|33791862}}</ref> Pediatric multisystem SARS COV2 with versus without cardiac involvement: a multicenter study from Latin America #MMPMID33791862 Pignatelli R; Antona CV; Rivera IR; Zenteno PA; Acosta YT; Huertas-Quinones M; Murillo CA; Torres FM; Cabalin CF; Camacho AG; Perez AA; Lombardi AB; Soares AM; Garcia CT; Borges CT; Villalba CN; Lechado CR; Dias DT; Morales DA; Copete EM; Goldenberg GL; Salazar JS; Moreira JA; Asakura J; Sabando KS; Branco KC; Rosas LT; Duarte MP; Carbajal MJ; Hernandez MR; Martinez MM; Echeverria NG; Caneva OM; Sepulveda PR; Diaz PA; Pluas RR; Alvarado TC; Faundes LT; Diaz YB; Zachariah JP Eur J Pediatr 2021[Sep]; 180 (9): 2879-2888 PMID33791862show ga Latin America (LATAM) children offer special insight into Severe Acute Respiratory Syndrome Coronavirus 2 (SARS COV2) due to high-risk race/ethnicity, variability in medical resources, diverse socioeconomic background, and numerous involved organ systems. This multinational study of LATAM youth examined the distinguishing features of acute or late multisystem SARS COV2 with versus without cardiac involvement. A consecutive sample of youth 0-18 years old (N = 98;50% male) presenting with multisystem SARS COV2 to 32 centers in 10 Latin American countries participating in a pediatric cardiac multi-imaging society were grouped as with versus without cardiac involvement, defined as abnormal echocardiographic findings or arrhythmia. Collected clinical data were analyzed by Student's t-test or Fisher's exact test. Cardiac (N = 48, 50% male) versus no cardiac (N = 50, 50% male) were similar in age; weight; nonrespiratory symptoms; and medical history. The cardiac group had 1 death and symptoms including coronary artery dilation, ejection fraction <50%, pericardial effusion, peripheral edema, arrhythmia, and pulmonary artery thrombus. The cardiac group had higher risk of ICU admission (77% vs 54%, p = 0.02); invasive ventilation (23% vs 4%,p = 0.007); vasoactive infusions (27% vs 4%, p = 0.002); prominent respiratory symptoms (60% vs 36%, p < 0.03); abnormal chest imaging (69% vs 34%, p = 0.001); troponin (33% vs 12%, p = 0.01); alanine aminotransferase (33% vs 12%, p = 0.02); and thrombocytopenia (46% vs 22%, p = 0.02). Receiver operating curve analysis showed that abnormal laboratories had 94% sensitivity and 98% negative predictive value on the need for ICU interventions.Conclusion: In LATAM children with multisystem SARS COV2, cardiac involvement was prevalent. Cardiac involvement was more likely to require ICU interventions, certain abnormal labs, and respiratory involvement. What is Known: * SARS COV2 can be asymptomatic in children but in some cases can have serious multisystemic involvement. * Hispanic ethnicity is purportedly at high risk of SARS COV2 in nations where they are often disadvantaged minority populations. What is New: * Latin American children presenting with multisystem SARS COV2 frequently have cardiac involvement which was associated with ICU interventions; prominent respiratory symptoms; abnormal chest X-ray; elevated troponin, ALT, and thrombocytopenia. * Elevated troponin, ALT or thrombocytopenia had high sensitivity and negative predictive value on the need for intensive care interventions. |*COVID-19[MESH] |*SARS-CoV-2[MESH] |Adolescent[MESH] |Arrhythmias, Cardiac[MESH] |Child[MESH] |Child, Preschool[MESH] |Critical Care[MESH] |Female[MESH] |Humans[MESH] |Infant[MESH] |Infant, Newborn[MESH] |Latin America/epidemiology[MESH]Pediatric multisystem SARS COV2 with versus without cardiac involvemen(epmc).pdf DeepDyve Pubget Overpricing