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10.1038/s41598-021-86853-4

http://scihub22266oqcxt.onion/10.1038/s41598-021-86853-4
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33790365!8012638!33790365
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suck abstract from ncbi


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pmid33790365      Sci+Rep 2021 ; 11 (1): 7310
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  • Risk factors on admission associated with hospital length of stay in patients with COVID-19: a retrospective cohort study #MMPMID33790365
  • Guo A; Lu J; Tan H; Kuang Z; Luo Y; Yang T; Xu J; Yu J; Wen C; Shen A
  • Sci Rep 2021[Mar]; 11 (1): 7310 PMID33790365show ga
  • Treating patients with COVID-19 is expensive, thus it is essential to identify factors on admission associated with hospital length of stay (LOS) and provide a risk assessment for clinical treatment. To address this, we conduct a retrospective study, which involved patients with laboratory-confirmed COVID-19 infection in Hefei, China and being discharged between January 20 2020 and March 16 2020. Demographic information, clinical treatment, and laboratory data for the participants were extracted from medical records. A prolonged LOS was defined as equal to or greater than the median length of hospitable stay. The median LOS for the 75 patients was 17 days (IQR 13-22). We used univariable and multivariable logistic regressions to explore the risk factors associated with a prolonged hospital LOS. Adjusted odds ratios (aORs) and 95% confidence intervals (CIs) were estimated. The median age of the 75 patients was 47 years. Approximately 75% of the patients had mild or general disease. The univariate logistic regression model showed that female sex and having a fever on admission were significantly associated with longer duration of hospitalization. The multivariate logistic regression model enhances these associations. Odds of a prolonged LOS were associated with male sex (aOR 0.19, 95% CI 0.05-0.63, p = 0.01), having fever on admission (aOR 8.27, 95% CI 1.47-72.16, p = 0.028) and pre-existing chronic kidney or liver disease (aOR 13.73 95% CI 1.95-145.4, p = 0.015) as well as each 1-unit increase in creatinine level (aOR 0.94, 95% CI 0.9-0.98, p = 0.007). We also found that a prolonged LOS was associated with increased creatinine levels in patients with chronic kidney or liver disease (p < 0.001). In conclusion, female sex, fever, chronic kidney or liver disease before admission and increasing creatinine levels were associated with prolonged LOS in patients with COVID-19.
  • |*Length of Stay/statistics & numerical data[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/epidemiology/*etiology[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |China[MESH]
  • |Comorbidity[MESH]
  • |Creatinine/blood[MESH]
  • |Female[MESH]
  • |Fever/virology[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Multivariate Analysis[MESH]
  • |Renal Insufficiency, Chronic/epidemiology[MESH]
  • |Retrospective Studies[MESH]


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