Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText.
Kick-your-searchterm to multiple Engines kick-your-query now !>
A dictionary by aggregated review articles of nephrology, medicine and the life sciences
Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

suck abstract from ncbi


10.1139/gen-2020-0157

http://scihub22266oqcxt.onion/10.1139/gen-2020-0157
suck pdf from google scholar
33788636!ä!33788636

suck abstract from ncbi


Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
pmid33788636      Genome 2021 ; 64 (7): 665-678
Nephropedia Template TP

gab.com Text

Twit Text FOAVip

Twit Text #

English Wikipedia


  • A study on non-synonymous mutational patterns in structural proteins of SARS-CoV-2 #MMPMID33788636
  • Das JK; Roy S
  • Genome 2021[Jul]; 64 (7): 665-678 PMID33788636show ga
  • SARS-CoV-2 is mutating and creating divergent variants across the world. An in-depth investigation of the amino acid substitutions in the genomic signature of SARS-CoV-2 proteins is highly essential for understanding its host adaptation and infection biology. A total of 9587 SARS-CoV-2 structural protein sequences collected from 49 different countries are used to characterize protein-wise variants, substitution patterns (type and location), and major substitution changes. The majority of the substitutions are distinct, mostly in a particular location, and lead to a change in an amino acid's biochemical properties. In terms of mutational changes, envelope (E) and membrane (M) proteins are relatively more stable than nucleocapsid (N) and spike (S) proteins. Several co-occurrence substitutions are observed, particularly in S and N proteins. Substitution specific to active sub-domains reveals that heptapeptide repeat, fusion peptides, transmembrane in S protein, and N-terminal and C-terminal domains in the N protein are remarkably mutated. We also observe a few deleterious mutations in the above domains. The overall study on non-synonymous mutation in structural proteins of SARS-CoV-2 at the start of the pandemic indicates a diversity amongst virus sequences.
  • |Amino Acid Substitution[MESH]
  • |Amino Acids/chemistry[MESH]
  • |Coronavirus Envelope Proteins/chemistry/genetics[MESH]
  • |Coronavirus Nucleocapsid Proteins/chemistry/genetics[MESH]
  • |Humans[MESH]
  • |Mutation[MESH]
  • |Mutation Rate[MESH]
  • |Phosphoproteins/chemistry/genetics[MESH]
  • |SARS-CoV-2/*chemistry/genetics/isolation & purification[MESH]
  • |Spike Glycoprotein, Coronavirus/chemistry/genetics[MESH]
  • |Viral Matrix Proteins/chemistry/genetics[MESH]


  • DeepDyve
  • Pubget Overpricing
  • suck abstract from ncbi

    Linkout box