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10.1002/ptr.7092 http://scihub22266oqcxt.onion/10.1002/ptr.7092 33786876!8250405!33786876     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Phytother+Res 2021 ; 35 (8): 4258-4283 Nephropedia Template TP {{tp|p=33786876|t=2021. Flavonoids as potential phytotherapeutics to combat cytokine storm in SARS-CoV-2 |pdf=|usr=}}{{33786876}} gab.com Text Flavonoids as potential phytotherapeutics to combat cytokine storm in SARS-CoV-2 JO: Phytother Res http://www.kidney.de/pget.php?&tw=1&pmid=33786876 #FOAvip Emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, COVID-19, has become the global panic since December 2019, which urges the global healthcare professionals to identify novel therapeutics to counteract this pandemic. So far, there is no approved treatment available to control this public health issue; however, a few antiviral agents and repurposed drugs support the patients under medical supervision by compromising their adverse effects, especially in emergency conditions. Only a few vaccines have been approved to date. In this context, several plant natural products-based research studies are evidenced to play a crucial role in immunomodulation that can prevent the chances of infection as well as combat the cytokine release storm (CRS) generated during COVID-19 infection. In this present review, we have focused on flavonoids, especially epicatechin, epigallocatechin gallate, hesperidin, naringenin, quercetin, rutin, luteolin, baicalin, diosmin, ge nistein, biochanin A, and silymarin, which can counteract the virus-mediated elevated levels of inflammatory cytokines leading to multiple organ failure. In addition, a comprehensive discussion on available in silico, in vitro, and in vivo findings with critical analysis has also been evaluated, which might pave the way for further development of phytotherapeutics to identify the potential lead candidatetoward effective and safe management of the SARS-CoV-2 disease. Twit Text FOAVip Flavonoids as potential phytotherapeutics to combat cytokine storm in SARS-CoV-2 ????Phytother Res http://www.kidney.de/pget.php?&tw=1&pmid=33786876 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33786876 #FOAvip English Wikipedia <ref>{{Cite pmid|33786876}}</ref> Flavonoids as potential phytotherapeutics to combat cytokine storm in SARS-CoV-2 #MMPMID33786876 Gour A; Manhas D; Bag S; Gorain B; Nandi U Phytother Res 2021[Aug]; 35 (8): 4258-4283 PMID33786876show ga Emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, COVID-19, has become the global panic since December 2019, which urges the global healthcare professionals to identify novel therapeutics to counteract this pandemic. So far, there is no approved treatment available to control this public health issue; however, a few antiviral agents and repurposed drugs support the patients under medical supervision by compromising their adverse effects, especially in emergency conditions. Only a few vaccines have been approved to date. In this context, several plant natural products-based research studies are evidenced to play a crucial role in immunomodulation that can prevent the chances of infection as well as combat the cytokine release storm (CRS) generated during COVID-19 infection. In this present review, we have focused on flavonoids, especially epicatechin, epigallocatechin gallate, hesperidin, naringenin, quercetin, rutin, luteolin, baicalin, diosmin, ge nistein, biochanin A, and silymarin, which can counteract the virus-mediated elevated levels of inflammatory cytokines leading to multiple organ failure. In addition, a comprehensive discussion on available in silico, in vitro, and in vivo findings with critical analysis has also been evaluated, which might pave the way for further development of phytotherapeutics to identify the potential lead candidatetoward effective and safe management of the SARS-CoV-2 disease. |*COVID-19 Drug Treatment[MESH] |*Cytokine Release Syndrome/drug therapy[MESH] |Cytokines[MESH] |Flavonoids/*therapeutic use[MESH] |Humans[MESH]Flavonoids as potential phytotherapeutics to combat cytokine storm in (epmc).pdf DeepDyve Pubget Overpricing