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10.1038/s41598-021-86747-5 http://scihub22266oqcxt.onion/10.1038/s41598-021-86747-5 33785815!8010012!33785815     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33785815&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2021 ; 11 (1): 7217 Nephropedia Template TP {{tp|p=33785815|t=2021. Low HDL and high triglycerides predict COVID-19 severity |pdf=|usr=}}{{33785815}} gab.com Text Low HDL and high triglycerides predict COVID-19 severity JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33785815 #FOAvip Lipids are indispensable in the SARS-CoV-2 infection process. The clinical significance of plasma lipid profile during COVID-19 has not been rigorously evaluated. We aim to ascertain the association of the plasma lipid profile with SARS-CoV-2 infection clinical evolution. Observational cross-sectional study including 1411 hospitalized patients with COVID-19 and an available standard lipid profile prior (n: 1305) or during hospitalization (n: 297). The usefulness of serum total, LDL, non-HDL and HDL cholesterol to predict the COVID-19 prognosis (severe vs mild) was analysed. Patients with severe COVID-19 evolution had lower HDL cholesterol and higher triglyceride levels before the infection. The lipid profile measured during hospitalization also showed that a severe outcome was associated with lower HDL cholesterol levels and higher triglycerides. HDL cholesterol and triglyceride concentrations were correlated with ferritin and D-dimer levels but not with CRP levels. The presence of atherogenic dyslipidaemia during the infection was strongly and independently associated with a worse COVID-19 infection prognosis. The low HDL cholesterol and high triglyceride concentrations measured before or during hospitalization are strong predictors of a severe course of the disease. The lipid profile should be considered as a sensitive marker of inflammation and should be measured in patients with COVID-19. Twit Text FOAVip Low HDL and high triglycerides predict COVID-19 severity ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33785815 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33785815 #FOAvip English Wikipedia <ref>{{Cite pmid|33785815}}</ref> Low HDL and high triglycerides predict COVID-19 severity #MMPMID33785815 Masana L; Correig E; Ibarretxe D; Anoro E; Arroyo JA; Jerico C; Guerrero C; Miret M; Naf S; Pardo A; Perea V; Perez-Bernalte R; Plana N; Ramirez-Montesinos R; Royuela M; Soler C; Urquizu-Padilla M; Zamora A; Pedro-Botet J Sci Rep 2021[Mar]; 11 (1): 7217 PMID33785815show ga Lipids are indispensable in the SARS-CoV-2 infection process. The clinical significance of plasma lipid profile during COVID-19 has not been rigorously evaluated. We aim to ascertain the association of the plasma lipid profile with SARS-CoV-2 infection clinical evolution. Observational cross-sectional study including 1411 hospitalized patients with COVID-19 and an available standard lipid profile prior (n: 1305) or during hospitalization (n: 297). The usefulness of serum total, LDL, non-HDL and HDL cholesterol to predict the COVID-19 prognosis (severe vs mild) was analysed. Patients with severe COVID-19 evolution had lower HDL cholesterol and higher triglyceride levels before the infection. The lipid profile measured during hospitalization also showed that a severe outcome was associated with lower HDL cholesterol levels and higher triglycerides. HDL cholesterol and triglyceride concentrations were correlated with ferritin and D-dimer levels but not with CRP levels. The presence of atherogenic dyslipidaemia during the infection was strongly and independently associated with a worse COVID-19 infection prognosis. The low HDL cholesterol and high triglyceride concentrations measured before or during hospitalization are strong predictors of a severe course of the disease. The lipid profile should be considered as a sensitive marker of inflammation and should be measured in patients with COVID-19. |Aged[MESH] |COVID-19/blood/*etiology[MESH] |Cholesterol, HDL/*blood[MESH] |Female[MESH] |Ferritins/blood[MESH] |Fibrin Fibrinogen Degradation Products/analysis[MESH] |Hospitalization[MESH] |Humans[MESH] |Lipids/blood[MESH] |Male[MESH] |Middle Aged[MESH] |Severity of Illness Index[MESH]Low HDL and high triglycerides predict COVID-19 severity (epmc).pdf DeepDyve Pubget Overpricing