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10.1007/s10096-021-04232-3

http://scihub22266oqcxt.onion/10.1007/s10096-021-04232-3
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33782783!8007057!33782783
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suck abstract from ncbi


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pmid33782783      Eur+J+Clin+Microbiol+Infect+Dis 2021 ; 40 (10): 2235-2241
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  • Performance of 30 commercial SARS-CoV-2 serology assays in testing symptomatic COVID-19 patients #MMPMID33782783
  • Vauloup-Fellous C; Maylin S; Perillaud-Dubois C; Brichler S; Alloui C; Gordien E; Rameix-Welti MA; Gault E; Moreau F; Fourati S; Challine D; Pawlotsky JM; Houhou-Fidouh N; Damond F; Mackiewicz V; Charpentier C; Meritet JF; Rozenberg F; Podglajen I; Marot S; Petit H; Burrel S; Akhavan S; Leruez-Ville M; Avettand-Fenoel V; Fourgeaud J; Guilleminot T; Gardiennet E; Bonacorsi S; Carol A; Carcelain G; Villemonteix J; Boukli N; Gozlan J; Morand-Joubert L; Legoff J; Delaugerre C; Chaix ML; Roque-Afonso AM; Dortet L; Naas T; Ronat JB; Lepape S; Marcelin AG; Descamps D
  • Eur J Clin Microbiol Infect Dis 2021[Oct]; 40 (10): 2235-2241 PMID33782783show ga
  • We report evaluation of 30 assays' (17 rapid tests (RDTs) and 13 automated/manual ELISA/CLIA assay (IAs)) clinical performances with 2594 sera collected from symptomatic patients with positive SARS-CoV-2 rRT-PCR on a respiratory sample, and 1996 pre-epidemic serum samples expected to be negative. Only 4 RDT and 3 IAs fitted both specificity (> 98%) and sensitivity (> 90%) criteria according to French recommendations. Serology may offer valuable information during COVID-19 pandemic, but inconsistent performances observed among the 30 commercial assays evaluated, which underlines the importance of independent evaluation before clinical implementation.
  • |Antibodies, Viral/*blood[MESH]
  • |COVID-19 Serological Testing/*methods[MESH]
  • |COVID-19/*blood/virology[MESH]
  • |Humans[MESH]
  • |Immunoassay/economics/*methods[MESH]
  • |Immunoglobulin M/blood[MESH]
  • |Reagent Kits, Diagnostic[MESH]
  • |SARS-CoV-2/genetics/*immunology/isolation & purification[MESH]


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