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Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Nat+Med 2021 ; 27 (5): 790-792 Nephropedia Template TP
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Initial report of decreased SARS-CoV-2 viral load after inoculation with the BNT162b2 vaccine #MMPMID33782619
Levine-Tiefenbrun M; Yelin I; Katz R; Herzel E; Golan Z; Schreiber L; Wolf T; Nadler V; Ben-Tov A; Kuint J; Gazit S; Patalon T; Chodick G; Kishony R
Nat Med 2021[May]; 27 (5): 790-792 PMID33782619show ga
Beyond their substantial protection of individual vaccinees, coronavirus disease 2019 (COVID-19) vaccines might reduce viral load in breakthrough infection and thereby further suppress onward transmission. In this analysis of a real-world dataset of positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test results after inoculation with the BNT162b2 messenger RNA vaccine, we found that the viral load was substantially reduced for infections occurring 12-37 d after the first dose of vaccine. These reduced viral loads hint at a potentially lower infectiousness, further contributing to vaccine effect on virus spread.