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10.1016/j.phrs.2021.105581 http://scihub22266oqcxt.onion/10.1016/j.phrs.2021.105581 33781873!7997688!33781873     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pharmacol+Res 2021 ; 168 (ä): 105581 Nephropedia Template TP {{tp|p=33781873|t=2021. Understanding the heart-brain axis response in COVID-19 patients: A suggestive perspective for therapeutic development |pdf=|usr=}}{{33781873}} gab.com Text Understanding the heart-brain axis response in COVID-19 patients: A suggestive perspective for therapeutic development JO: Pharmacol Res http://www.kidney.de/pget.php?&tw=1&pmid=33781873 #FOAvip In-depth characterization of heart-brain communication in critically ill patients with severe acute respiratory failure is attracting significant interest in the COronaVIrus Disease 19 (COVID-19) pandemic era during intensive care unit (ICU) stay and after ICU or hospital discharge. Emerging research has provided new insights into pathogenic role of the deregulation of the heart-brain axis (HBA), a bidirectional flow of information, in leading to severe multiorgan disease syndrome (MODS) in patients with confirmed infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Noteworthy, HBA dysfunction may worsen the outcome of the COVID-19 patients. In this review, we discuss the critical role HBA plays in both promoting and limiting MODS in COVID-19. We also highlight the role of HBA as new target for novel therapeutic strategies in COVID-19 in order to open new translational frontiers of care. This is a translational perspective from the Italian Society of Cardiovascular Researches. Twit Text FOAVip Understanding the heart-brain axis response in COVID-19 patients: A suggestive perspective for therapeutic development ????Pharmacol Res http://www.kidney.de/pget.php?&tw=1&pmid=33781873 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33781873 #FOAvip English Wikipedia <ref>{{Cite pmid|33781873}}</ref> Understanding the heart-brain axis response in COVID-19 patients: A suggestive perspective for therapeutic development #MMPMID33781873 Lionetti V; Bollini S; Coppini R; Gerbino A; Ghigo A; Iaccarino G; Madonna R; Mangiacapra F; Miragoli M; Moccia F; Munaron L; Pagliaro P; Parenti A; Pasqua T; Penna C; Quaini F; Rocca C; Samaja M; Sartiani L; Soda T; Tocchetti CG; Angelone T Pharmacol Res 2021[Jun]; 168 (ä): 105581 PMID33781873show ga In-depth characterization of heart-brain communication in critically ill patients with severe acute respiratory failure is attracting significant interest in the COronaVIrus Disease 19 (COVID-19) pandemic era during intensive care unit (ICU) stay and after ICU or hospital discharge. Emerging research has provided new insights into pathogenic role of the deregulation of the heart-brain axis (HBA), a bidirectional flow of information, in leading to severe multiorgan disease syndrome (MODS) in patients with confirmed infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Noteworthy, HBA dysfunction may worsen the outcome of the COVID-19 patients. In this review, we discuss the critical role HBA plays in both promoting and limiting MODS in COVID-19. We also highlight the role of HBA as new target for novel therapeutic strategies in COVID-19 in order to open new translational frontiers of care. This is a translational perspective from the Italian Society of Cardiovascular Researches. |Adrenal Cortex Hormones/administration & dosage[MESH] |Anti-Inflammatory Agents/administration & dosage[MESH] |Antiviral Agents/administration & dosage[MESH] |Brain Diseases/immunology/metabolism/*therapy[MESH] |Brain/*drug effects/immunology/metabolism[MESH] |COVID-19/immunology/metabolism/*therapy[MESH] |Critical Care/methods[MESH] |Critical Illness/therapy[MESH] |Dietary Supplements[MESH] |Functional Food[MESH] |Heart Diseases/immunology/metabolism/*therapy[MESH] |Heart/*drug effects[MESH] |Humans[MESH] |Inflammation Mediators/antagonists & inhibitors/immunology/metabolism[MESH] |Microvessels/drug effects/immunology/metabolism[MESH] |Multiple Organ Failure/immunology/metabolism/therapy[MESH]Understanding the heart-brain axis response in COVID-19 patients: A su(epmc).pdf DeepDyve Pubget Overpricing