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10.1186/s13063-021-05209-5 http://scihub22266oqcxt.onion/10.1186/s13063-021-05209-5 33781304!8006114!33781304     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trials 2021 ; 22 (1): 234 Nephropedia Template TP {{tp|p=33781304|t=2021. COVID-19: underpowered randomised trials, or no randomised trials?|pdf=|usr=}}{{33781304}} gab.com Text COVID-19: underpowered randomised trials, or no randomised trials JO: Trials http://www.kidney.de/pget.php?&tw=1&pmid=33781304 #FOAvip A recently published trial of face mask use to protect against COVID-19 demonstrated a key barrier to carrying out randomised trials in public health: the need for unattainably large sample sizes. For many public health interventions, the choice is not between sufficiently powered trials and underpowered trials, but between underpowered trials and no trials at all. Underpowered trials should be viewed as contributions to the larger body of evidence, alongside other studies of various sizes and designs, collectively assessed and synthesized in systematic reviews. Overemphasis on sample size calculation is probably more of a hindrance than a help to scientific progress. Twit Text FOAVip COVID-19: underpowered randomised trials, or no randomised trials ????Trials http://www.kidney.de/pget.php?&tw=1&pmid=33781304 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33781304 #FOAvip English Wikipedia <ref>{{Cite pmid|33781304}}</ref> COVID-19: underpowered randomised trials, or no randomised trials? #MMPMID33781304 Fretheim A Trials 2021[Mar]; 22 (1): 234 PMID33781304show ga A recently published trial of face mask use to protect against COVID-19 demonstrated a key barrier to carrying out randomised trials in public health: the need for unattainably large sample sizes. For many public health interventions, the choice is not between sufficiently powered trials and underpowered trials, but between underpowered trials and no trials at all. Underpowered trials should be viewed as contributions to the larger body of evidence, alongside other studies of various sizes and designs, collectively assessed and synthesized in systematic reviews. Overemphasis on sample size calculation is probably more of a hindrance than a help to scientific progress. |*COVID-19[MESH] |Humans[MESH] |Masks[MESH] |SARS-CoV-2[MESH]COVID-19: underpowered randomised trials, or no randomised trials?(epmc).pdf DeepDyve Pubget Overpricing