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10.1097/PEC.0000000000002380

http://scihub22266oqcxt.onion/10.1097/PEC.0000000000002380
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33780408!ä!33780408

suck abstract from ncbi


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pmid33780408      Pediatr+Emerg+Care 2021 ; 37 (4): 232-236
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  • Risk of Serious Bacterial Infections in Young Febrile Infants With COVID-19 #MMPMID33780408
  • Payson A; Etinger V; Napky P; Montarroyos S; Ruiz-Castaneda A; Mestre M
  • Pediatr Emerg Care 2021[Apr]; 37 (4): 232-236 PMID33780408show ga
  • OBJECTIVES: The purposes of this study were to describe the clinical characteristics of febrile infants younger than 90 days with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, to investigate the prevalence of serious bacterial infections (SBIs) in these infants, and to compare the risk of SBI in SARS-CoV-2-positive febrile infants with sex- and age-matched SARS-CoV- 2-negative febrile infants. METHODS: This was a retrospective cohort study conducted from March to November 2020 in a tertiary children's hospital. Patients were identified by International Classification of Diseases, 10th Revision codes and included if age was younger than 90 days, a SARS-CoV-2 test was performed, and at least 1 bacterial culture was collected. Positive cases of SARS-CoV-2 were age- and sex-matched to negative controls for analysis. Serious bacterial infection was defined as a urinary tract infection, bacterial enteritis, bacteremia, and/or bacterial meningitis. RESULTS: Fifty-three SARS-CoV-2-positive infants were identified with a higher rate of respiratory symptoms and lower white blood cell and C-reactive protein values than their SARS-CoV-2 matched controls. The rate of SBI in the SARS-CoV-2-positive infants was 8% compared with 34% in the controls; the most common infections were urinary tract infections (6% vs 23%). There were no cases of bacteremia or bacterial meningitis in the COVID-19 (coronavirus disease 2019) infants and 2 (4%) cases of bacteremia in the controls. The relative risk of any SBI between the 2 groups was 0.22 (95% confidence interval, 0.1-0.6; P
  • |*SARS-CoV-2[MESH]
  • |Bacterial Infections/epidemiology/*etiology[MESH]
  • |COVID-19/complications/*epidemiology[MESH]
  • |Emergency Service, Hospital/*statistics & numerical data[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Infant, Newborn[MESH]
  • |Male[MESH]
  • |Prevalence[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Assessment/*methods[MESH]


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