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10.1007/s00508-021-01845-8

http://scihub22266oqcxt.onion/10.1007/s00508-021-01845-8
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suck abstract from ncbi


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pmid33779831      Wien+Klin+Wochenschr 2021 ; 133 (17-18): 958-965
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  • The advantages of drug treatment with statins in patients with SARS-CoV-2 infection #MMPMID33779831
  • Ferrara F; Vitiello A
  • Wien Klin Wochenschr 2021[Sep]; 133 (17-18): 958-965 PMID33779831show ga
  • On 11 March 2020 the World Health Organization (WHO) declared a status of global pandemic caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease 2019, COVID-19). The pandemic is currently underway, and to date has caused approximately 2.42 million deaths worldwide. The first vaccines have recently been licensed; however, research continues to identify therapeutic agents to prevent serious complications, such as anti-inflammatory, immunomodulatory, anticoagulant or antiviral agents authorized for other therapeutic indications. Epidemiological evidence shows that advanced age and comorbidities, such as diabetes, heart disease, and dyslipidemia may represent COVID-19 risk factors. In particular, in patients with hypercholesterolemia treated with statins, it is recommended that treatment should not be discontinued if COVID-19 infection occurs. The pleiotropic effects of statins are well known. In this brief review, we propose that the use of statins can potentially protect against SARS-CoV-2-induced tissue damage and improve lung function in COVID-19 patients through several pleiotropic effects. Pleiotropic effects of statins that may be a significant benefit in patients with hypercholesterolemia treated with statins and COVID-19 positive. Recent evidence shows promising results.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use[MESH]
  • |*Pharmaceutical Preparations[MESH]
  • |Humans[MESH]


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