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10.1007/s00296-021-04819-1 http://scihub22266oqcxt.onion/10.1007/s00296-021-04819-1 33774723!8000693!33774723     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Rheumatol+Int 2021 ; 41 (6): 1021-1036 Nephropedia Template TP {{tp|p=33774723|t=2021. Understanding and managing anti-MDA 5 dermatomyositis, including potential COVID-19 mimicry |pdf=|usr=}}{{33774723}} gab.com Text Understanding and managing anti-MDA 5 dermatomyositis, including potential COVID-19 mimicry JO: Rheumatol Int http://www.kidney.de/pget.php?&tw=1&pmid=33774723 #FOAvip Anti-Melanoma Differentiation-Associated gene 5 (MDA-5) Dermatomyositis (MDA5, DM) is a recently identified subtype of myositis characteristically associated with Rapidly Progressive Interstitial Lung Disease (RP-ILD) and unique cutaneous features. We reviewed PubMed, SCOPUS and Web of Science databases and selected 87 relevant articles after screening 1485 search results, aiming to gain a better understanding of the pathophysiology, clinical features, diagnosis, and treatment approaches of anti-MDA-5 DM described in the literature. The etiopathogenesis is speculatively linked to an unidentified viral trigger on the background of genetic predisposition culminating in an acquired type I interferonopathy. The clinical phenotype is highly varied in different ethnicities, with new clinical features having been recently described, expanding the spectrum of cases that should raise the suspicion of anti-MDA-5 DM. Unfortunately, the diagnosis is frequently missed despite excessive mortality, calling for wider awareness of suspect symptoms. RP ILD is the major determinant of survival, treatment being largely based on observational studies with recent insights into aggressive combined immunosuppression at the outset. Twit Text FOAVip Understanding and managing anti-MDA 5 dermatomyositis, including potential COVID-19 mimicry ????Rheumatol Int http://www.kidney.de/pget.php?&tw=1&pmid=33774723 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33774723 #FOAvip English Wikipedia <ref>{{Cite pmid|33774723}}</ref> Understanding and managing anti-MDA 5 dermatomyositis, including potential COVID-19 mimicry #MMPMID33774723 Mehta P; Machado PM; Gupta L Rheumatol Int 2021[Jun]; 41 (6): 1021-1036 PMID33774723show ga Anti-Melanoma Differentiation-Associated gene 5 (MDA-5) Dermatomyositis (MDA5, DM) is a recently identified subtype of myositis characteristically associated with Rapidly Progressive Interstitial Lung Disease (RP-ILD) and unique cutaneous features. We reviewed PubMed, SCOPUS and Web of Science databases and selected 87 relevant articles after screening 1485 search results, aiming to gain a better understanding of the pathophysiology, clinical features, diagnosis, and treatment approaches of anti-MDA-5 DM described in the literature. The etiopathogenesis is speculatively linked to an unidentified viral trigger on the background of genetic predisposition culminating in an acquired type I interferonopathy. The clinical phenotype is highly varied in different ethnicities, with new clinical features having been recently described, expanding the spectrum of cases that should raise the suspicion of anti-MDA-5 DM. Unfortunately, the diagnosis is frequently missed despite excessive mortality, calling for wider awareness of suspect symptoms. RP ILD is the major determinant of survival, treatment being largely based on observational studies with recent insights into aggressive combined immunosuppression at the outset. |COVID-19/diagnosis[MESH] |Dermatomyositis/*diagnosis/epidemiology/*therapy/virology[MESH] |Disease Progression[MESH] |Exanthema/diagnosis/etiology/virology[MESH] |Female[MESH] |Humans[MESH] |Interferon-Induced Helicase, IFIH1[MESH] |Lung Diseases, Interstitial/diagnosis/etiology/virology[MESH] |Male[MESH] |Prevalence[MESH]Understanding and managing anti-MDA 5 dermatomyositis, including poten(epmc).pdf DeepDyve Pubget Overpricing