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10.1159/000515341

http://scihub22266oqcxt.onion/10.1159/000515341
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33774628!8089426!33774628
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suck abstract from ncbi


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pmid33774628      Chemotherapy 2021 ; 66 (1-2): 8-16
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  • Animal Hosts and Experimental Models of SARS-CoV-2 Infection #MMPMID33774628
  • Parolin C; Virtuoso S; Giovanetti M; Angeletti S; Ciccozzi M; Borsetti A
  • Chemotherapy 2021[]; 66 (1-2): 8-16 PMID33774628show ga
  • Viruses arise through cross-species transmission and can cause potentially fatal diseases in humans. This is the case of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which recently appeared in Wuhan, China, and rapidly spread worldwide, causing the outbreak of coronavirus disease 2019 (COVID-19) and posing a global health emergency. Sequence analysis and epidemiological investigations suggest that the most likely original source of SARS-CoV-2 is a spillover from an animal reservoir, probably bats, that infected humans either directly or through intermediate animal hosts. The role of animals as reservoirs and natural hosts in SARS-CoV-2 has to be explored, and animal models for COVID-19 are needed as well to be evaluated for countermeasures against SARS-CoV-2 infection. Experimental cells, tissues, and animal models that are currently being used and developed in COVID-19 research will be presented.
  • |*COVID-19/prevention & control/transmission/virology[MESH]
  • |*Disease Vectors[MESH]
  • |*SARS-CoV-2/isolation & purification/pathogenicity[MESH]
  • |Animals[MESH]
  • |Communicable Disease Control/*methods[MESH]
  • |Disease Reservoirs/*virology[MESH]
  • |Disease Transmission, Infectious/prevention & control[MESH]
  • |Humans[MESH]


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