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10.1016/j.annemergmed.2020.12.007

http://scihub22266oqcxt.onion/10.1016/j.annemergmed.2020.12.007
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suck abstract from ncbi


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pmid33771413      Ann+Emerg+Med 2021 ; 78 (1): 27-34
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  • Diagnosed and Undiagnosed COVID-19 in US Emergency Department Health Care Personnel: A Cross-sectional Analysis #MMPMID33771413
  • Mohr NM; Harland KK; Krishnadasan A; Eyck PT; Mower WR; Willey J; Chisolm-Straker M; Lim SC; McDonald LC; Kutty PK; Hesse E; Santibanez S; Talan DA
  • Ann Emerg Med 2021[Jul]; 78 (1): 27-34 PMID33771413show ga
  • STUDY OBJECTIVE: We determine the percentage of diagnosed and undiagnosed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among a sample of US emergency department (ED) health care personnel before July 2020. METHODS: This was a cross-sectional analysis of ED health care personnel in 20 geographically diverse university-affiliated EDs from May 13, to July 8, 2020, including case counts of prior laboratory-confirmed coronavirus disease 2019 (COVID-19) diagnoses among all ED health care personnel, and then point-in-time serology (with confirmatory testing) and reverse transcriptase-polymerase chain reaction testing in a sample of volunteers without a previous COVID-19 diagnosis. Health care staff were categorized as clinical (physicians, advanced practice providers, and nurses) and nonclinical (clerks, social workers, and case managers). Previously undiagnosed infection was based on positive SARS-CoV-2 serology or reverse transcriptase-polymerase chain reaction result among health care personnel without prior diagnosis. RESULTS: Diagnosed COVID-19 occurred in 2.8% of health care personnel (193/6,788), and the prevalence was similar for nonclinical and clinical staff (3.8% versus 2.7%; odds ratio 1.5; 95% confidence interval 0.7 to 3.2). Among 1,606 health care personnel without previously diagnosed COVID-19, 29 (1.8%) had evidence of current or past SARS-CoV-2 infection. Most (62%; 18/29) who were seropositive did not think they had been infected, 76% (19/25) recalled COVID-19-compatible symptoms, and 89% (17/19) continued to work while symptomatic. Accounting for both diagnosed and undiagnosed infections, 4.6% (95% confidence interval 2.8% to 7.5%) of ED health care personnel were estimated to have been infected with SARS-CoV-2, with 38% of those infections undiagnosed. CONCLUSION: In late spring and early summer 2020, the estimated prevalence of severe acute respiratory syndrome coronavirus 2 infection was 4.6%, and greater than one third of infections were undiagnosed. Undiagnosed SARS-CoV-2 infection may pose substantial risk for transmission to other staff and patients.
  • |*SARS-CoV-2[MESH]
  • |Adult[MESH]
  • |COVID-19/diagnosis/*epidemiology[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Emergency Service, Hospital/*statistics & numerical data[MESH]
  • |Female[MESH]
  • |Health Personnel/*statistics & numerical data[MESH]
  • |Hospitals, University/statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Prevalence[MESH]


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