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10.2807/1560-7917.ES.2021.26.12.2100329

http://scihub22266oqcxt.onion/10.2807/1560-7917.ES.2021.26.12.2100329
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33769252!7995559!33769252
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suck abstract from ncbi


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pmid33769252      Euro+Surveill 2021 ; 26 (12): ä
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  • Robust antibody responses in 70-80-year-olds 3 weeks after the first or second doses of Pfizer/BioNTech COVID-19 vaccine, United Kingdom, January to February 2021 #MMPMID33769252
  • Subbarao S; Warrener LA; Hoschler K; Perry KR; Shute J; Whitaker H; O'Brien M; Baawuah F; Moss P; Parry H; Ladhani SN; Ramsay ME; Brown KE; Amirthalingam G
  • Euro Surveill 2021[Mar]; 26 (12): ä PMID33769252show ga
  • Sera were collected from 185 adults aged >/= 70 years in London to evaluate the immune response to COVID-19 vaccines. A single dose of Pfizer/BioNtech vaccine resulted in > 94% seropositivity after 3 weeks in naive individuals using the Roche Spike antibody assay, while two doses produced very high spike antibody levels, significantly higher than convalescent sera from mild-to-moderate PCR-confirmed adult cases. Our findings support the United Kingdom's approach of prioritising the first dose and delaying the second dose of COVID-19 vaccine.
  • |*Antibody Formation[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Antibodies, Viral/*blood[MESH]
  • |COVID-19 Vaccines/*immunology[MESH]
  • |COVID-19/*prevention & control[MESH]
  • |Humans[MESH]


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