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Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Euro+Surveill 2021 ; 26 (12): ä Nephropedia Template TP
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Robust antibody responses in 70-80-year-olds 3 weeks after the first or second doses of Pfizer/BioNTech COVID-19 vaccine, United Kingdom, January to February 2021 #MMPMID33769252
Subbarao S; Warrener LA; Hoschler K; Perry KR; Shute J; Whitaker H; O'Brien M; Baawuah F; Moss P; Parry H; Ladhani SN; Ramsay ME; Brown KE; Amirthalingam G
Euro Surveill 2021[Mar]; 26 (12): ä PMID33769252show ga
Sera were collected from 185 adults aged >/= 70 years in London to evaluate the immune response to COVID-19 vaccines. A single dose of Pfizer/BioNtech vaccine resulted in > 94% seropositivity after 3 weeks in naive individuals using the Roche Spike antibody assay, while two doses produced very high spike antibody levels, significantly higher than convalescent sera from mild-to-moderate PCR-confirmed adult cases. Our findings support the United Kingdom's approach of prioritising the first dose and delaying the second dose of COVID-19 vaccine.