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10.1002/eji.202049046

http://scihub22266oqcxt.onion/10.1002/eji.202049046
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33768543!8250259!33768543
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suck abstract from ncbi


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pmid33768543      Eur+J+Immunol 2021 ; 51 (6): 1535-1538
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  • Enrichment of CCR6(+) CD8(+) T cells and CCL20 in the lungs of mechanically ventilated patients with COVID-19 #MMPMID33768543
  • Saris A; Reijnders TDY; Reijm M; Hollander JC; de Buck K; Schuurman AR; Duitman J; Heunks L; Aman J; Bogaard HJ; Nossent EJ; van der Poll T; Bontkes HJ
  • Eur J Immunol 2021[Jun]; 51 (6): 1535-1538 PMID33768543show ga
  • Despite high levels of CXCR3 ligands in mechanically ventilated COVID-19 patients, BALF CD8 T cells were not enriched in CXCR3(+) cells but rather CCR6(+) , likely due to high CCL20 levels in BALF, and had very high PD-1 expression. In mechanically ventilated, but not ward, patients Th-1 immunity is impaired. ?.
  • |*Respiration, Artificial[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |CD8-Positive T-Lymphocytes/*immunology/pathology[MESH]
  • |COVID-19/*immunology/pathology/therapy[MESH]
  • |Chemokine CCL20/*immunology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lung/*immunology/pathology[MESH]
  • |Lymphocyte Count[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Receptors, CCR6/*immunology[MESH]


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