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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Eur+J+Immunol 2021 ; 51 (6): 1535-1538 Nephropedia Template TP
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Enrichment of CCR6(+) CD8(+) T cells and CCL20 in the lungs of mechanically ventilated patients with COVID-19 #MMPMID33768543
Saris A; Reijnders TDY; Reijm M; Hollander JC; de Buck K; Schuurman AR; Duitman J; Heunks L; Aman J; Bogaard HJ; Nossent EJ; van der Poll T; Bontkes HJ
Eur J Immunol 2021[Jun]; 51 (6): 1535-1538 PMID33768543show ga
Despite high levels of CXCR3 ligands in mechanically ventilated COVID-19 patients, BALF CD8 T cells were not enriched in CXCR3(+) cells but rather CCR6(+) , likely due to high CCL20 levels in BALF, and had very high PD-1 expression. In mechanically ventilated, but not ward, patients Th-1 immunity is impaired. ?.