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10.1007/s10072-021-05180-8

http://scihub22266oqcxt.onion/10.1007/s10072-021-05180-8
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33768436!7994064!33768436
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suck abstract from ncbi


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pmid33768436      Neurol+Sci 2021 ; 42 (12): 5087-5092
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  • Effects of the onabotulinumtoxinA follow-up delay in migraine course during the COVID-19 lockdown #MMPMID33768436
  • Gonzalez-Martinez A; Planchuelo-Gomez A; Guerrero AL; Garcia-Azorin D; Santos-Lasaosa S; Navarro-Perez MP; Odriozola-Gonzalez P; Irurtia MJ; Quintas S; de Luis-Garcia R; Gago-Veiga AB
  • Neurol Sci 2021[Dec]; 42 (12): 5087-5092 PMID33768436show ga
  • BACKGROUND: Face-to-face procedures have been postponed during COVID-19 pandemic. We aim to evaluate the impact of onabotulinumtoxinA follow-up delay in migraine during COVID-19 pandemic. METHODS: Subjective worsening, intensity of migraine attacks, and frequency of headache and migraine were retrospectively compared between patients with unmodified and interrupted onabotulinumtoxinA follow-up in Headache Units. RESULTS: We included 67 patients with chronic migraine or high-frequency episodic migraine under onabotulinumtoxinA treatment, 65 (97.0%) female, 44.5 +/- 12.1 years old. Treatment administration was voluntarily delayed in 14 (20.9%) patients and nine (13.4%) were unable to continue follow-up. Patients with uninterrupted follow-up during lockdown presented 7.6 and 8.1 less monthly days with headache (adjusted p = 0.017) and migraine attacks (adjusted p = 0.009) compared to patients whose follow-up was interrupted, respectively. CONCLUSION: Involuntary delay of onabotulinumtoxinA follow-up in patients with migraine due to COVID-19 pandemic was associated with a higher frequency of headache and migraine attacks. Safe administration of onabotulinumtoxinA during lockdown should be promoted.
  • |*Botulinum Toxins, Type A[MESH]
  • |*COVID-19[MESH]
  • |*Migraine Disorders/drug therapy/epidemiology[MESH]
  • |Adult[MESH]
  • |Chronic Disease[MESH]
  • |Communicable Disease Control[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Humans[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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