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10.1101/2021.03.04.21252945 http://scihub22266oqcxt.onion/10.1101/2021.03.04.21252945 33758879!7987038!33758879     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\33758879.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       medRxiv 2021 ; ä (ä): ä Nephropedia Template TP {{tp|p=33758879|t=2021. The COVIDome Explorer Researcher Portal |pdf=|usr=}}{{33758879}} gab.com Text The COVIDome Explorer Researcher Portal JO: medRxiv http://www.kidney.de/pget.php?&tw=1&pmid=33758879 #FOAvip COVID-19 pathology involves dysregulation of diverse molecular, cellular, and physiological processes. In order to expedite integrated and collaborative COVID-19 research, we completed multi-omics analysis of hospitalized COVID-19 patients including matched analysis of the whole blood transcriptome, plasma proteomics with two complementary platforms, cytokine profiling, plasma and red blood cell metabolomics, deep immune cell phenotyping by mass cytometry, and clinical data annotation. We refer to this multidimensional dataset as the COVIDome. We then created the COVIDome Explorer, an online researcher portal where the data can be analyzed and visualized in real time. We illustrate here the use of the COVIDome dataset through a multi-omics analysis of biosignatures associated with C-reactive protein (CRP), an established marker of poor prognosis in COVID-19, revealing associations between CRP levels and damage-associated molecular patterns, depletion of protective serpins, and mitochondrial metabolism dysregulation. We expect that the COVIDome Explorer will rapidly accelerate data sharing, hypothesis testing, and discoveries worldwide. Twit Text FOAVip The COVIDome Explorer Researcher Portal ????medRxiv http://www.kidney.de/pget.php?&tw=1&pmid=33758879 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33758879 #FOAvip English Wikipedia <ref>{{Cite pmid|33758879}}</ref> The COVIDome Explorer Researcher Portal #MMPMID33758879 Sullivan KD; Galbraith MD; Kinning KT; Bartsch K; Levinsky N; Araya P; Smith KP; Granrath RE; Shaw JR; Baxter R; Jordan KR; Russell S; Dzieciatkowska M; Reisz JA; Gamboni F; Cendali F; Ghosh T; Monte AA; Bennett TD; Miller MG; Hsieh EWY; D'Alessandro A; Hansen KC; Espinosa JM medRxiv 2021[Mar]; ä (ä): ä PMID33758879show ga COVID-19 pathology involves dysregulation of diverse molecular, cellular, and physiological processes. In order to expedite integrated and collaborative COVID-19 research, we completed multi-omics analysis of hospitalized COVID-19 patients including matched analysis of the whole blood transcriptome, plasma proteomics with two complementary platforms, cytokine profiling, plasma and red blood cell metabolomics, deep immune cell phenotyping by mass cytometry, and clinical data annotation. We refer to this multidimensional dataset as the COVIDome. We then created the COVIDome Explorer, an online researcher portal where the data can be analyzed and visualized in real time. We illustrate here the use of the COVIDome dataset through a multi-omics analysis of biosignatures associated with C-reactive protein (CRP), an established marker of poor prognosis in COVID-19, revealing associations between CRP levels and damage-associated molecular patterns, depletion of protective serpins, and mitochondrial metabolism dysregulation. We expect that the COVIDome Explorer will rapidly accelerate data sharing, hypothesis testing, and discoveries worldwide. äThe COVIDome Explorer Researcher Portal (epmc).pdf DeepDyve Pubget Overpricing