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10.1038/s41467-021-22034-1 http://scihub22266oqcxt.onion/10.1038/s41467-021-22034-1 33753738!7985370!33753738     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33753738&cmd=llinks): Failed to open stream: HTTP request failed! 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SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19 |pdf=|usr=}}{{33753738}} gab.com Text SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19 JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=33753738 #FOAvip Long-term antibody responses and neutralizing activities in response to SARS-CoV-2 infection are not yet clear. Here we quantify immunoglobulin M (IgM) and G (IgG) antibodies recognizing the SARS-CoV-2 receptor-binding domain (RBD) of the spike (S) or the nucleocapsid (N) protein, and neutralizing antibodies during a period of 6 months from COVID-19 disease onset in 349 symptomatic COVID-19 patients who were among the first be infected world-wide. The positivity rate and magnitude of IgM-S and IgG-N responses increase rapidly. High levels of IgM-S/N and IgG-S/N at 2-3 weeks after disease onset are associated with virus control and IgG-S titers correlate closely with the capacity to neutralize SARS-CoV-2. Although specific IgM-S/N become undetectable 12 weeks after disease onset in most patients, IgG-S/N titers have an intermediate contraction phase, but stabilize at relatively high levels over the 6 month observation period. At late time points, the positivity rates for binding and neutralizing SARS-CoV-2-specific antibodies are still >70%. These data indicate sustained humoral immunity in recovered patients who had symptomatic COVID-19, suggesting prolonged immunity. Twit Text FOAVip SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19 ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=33753738 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33753738 #FOAvip English Wikipedia <ref>{{Cite pmid|33753738}}</ref> SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19 #MMPMID33753738 Wu J; Liang B; Chen C; Wang H; Fang Y; Shen S; Yang X; Wang B; Chen L; Chen Q; Wu Y; Liu J; Yang X; Li W; Zhu B; Zhou W; Wang H; Li S; Lu S; Liu D; Li H; Krawczyk A; Lu M; Yang D; Deng F; Dittmer U; Trilling M; Zheng X Nat Commun 2021[Mar]; 12 (1): 1813 PMID33753738show ga Long-term antibody responses and neutralizing activities in response to SARS-CoV-2 infection are not yet clear. Here we quantify immunoglobulin M (IgM) and G (IgG) antibodies recognizing the SARS-CoV-2 receptor-binding domain (RBD) of the spike (S) or the nucleocapsid (N) protein, and neutralizing antibodies during a period of 6 months from COVID-19 disease onset in 349 symptomatic COVID-19 patients who were among the first be infected world-wide. The positivity rate and magnitude of IgM-S and IgG-N responses increase rapidly. High levels of IgM-S/N and IgG-S/N at 2-3 weeks after disease onset are associated with virus control and IgG-S titers correlate closely with the capacity to neutralize SARS-CoV-2. Although specific IgM-S/N become undetectable 12 weeks after disease onset in most patients, IgG-S/N titers have an intermediate contraction phase, but stabilize at relatively high levels over the 6 month observation period. At late time points, the positivity rates for binding and neutralizing SARS-CoV-2-specific antibodies are still >70%. These data indicate sustained humoral immunity in recovered patients who had symptomatic COVID-19, suggesting prolonged immunity. |Adult[MESH] |Aged[MESH] |Antibodies, Neutralizing/immunology[MESH] |Antibodies, Viral/immunology[MESH] |COVID-19/*immunology[MESH] |Female[MESH] |Humans[MESH] |Immunity, Humoral/immunology[MESH] |Immunoglobulin G/immunology[MESH] |Immunoglobulin M/immunology[MESH] |Male[MESH] |Middle Aged[MESH] |SARS-CoV-2/*immunology[MESH] |Severity of Illness Index[MESH]SARS-CoV-2 infection induces sustained humoral immune responses in con(epmc).pdf DeepDyve Pubget Overpricing