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10.1016/j.resinv.2021.02.006 http://scihub22266oqcxt.onion/10.1016/j.resinv.2021.02.006 33753011!ä!33753011 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Respir+Investig 2021 ; 59 (3): 302-311 Nephropedia Template TP {{tp|p=33753011|t=2021. Extracellular vesicles: Their emerging roles in the pathogenesis of respiratory diseases |pdf=|usr=}}{{33753011}} gab.com Text Extracellular vesicles: Their emerging roles in the pathogenesis of respiratory diseases JO: Respir Investig http://www.kidney.de/pget.php?&tw=1&pmid=33753011 #FOAvip Alveoli are the basic structure of the lungs, consisting of various types of parenchymal and bone marrow-derived cells including alveolar macrophages. These various types of cells have several important functions; thus, communication between these cells plays an important role in homeostasis as well as in the pathophysiology of diseases in the lungs. For a better understanding of the pathophysiology of lung diseases, researchers have isolated each type of lung cell to investigate the changes in their gene expressions, including their humoral factor or adhesion molecules, to reveal the intercellular communication among these cells. In particular, investigations during the past decade have focused on extracellular vesicles, which are lipid bilayer delimited vesicles released from a cell that can move among various cells and transfer substances, including microRNAs, mRNAs and proteins, thus, functioning as intercellular messengers. Extracellular vesicles can be classified into three general groups: apoptotic bodies, exosomes, and microparticles. Extracellular vesicles, especially exosomes and microparticles, are attracting increasing attention from pulmonologists as tools for understanding pathogenesis and disease diagnosis. Here, we review studies, including our own, on exosomes and microparticles and their roles in both lung homeostasis and the pathogenesis of lung diseases such as idiopathic pulmonary fibrosis, chronic obstructive lung diseases, and acute respiratory distress syndrome. This review also addresses the roles of extracellular vesicles in COVID-19, the current global public health crisis. Twit Text FOAVip Extracellular vesicles: Their emerging roles in the pathogenesis of respiratory diseases ????Respir Investig http://www.kidney.de/pget.php?&tw=1&pmid=33753011 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33753011 #FOAvip English Wikipedia <ref>{{Cite pmid|33753011}}</ref> Extracellular vesicles: Their emerging roles in the pathogenesis of respiratory diseases #MMPMID33753011 Yamada M Respir Investig 2021[May]; 59 (3): 302-311 PMID33753011show ga Alveoli are the basic structure of the lungs, consisting of various types of parenchymal and bone marrow-derived cells including alveolar macrophages. These various types of cells have several important functions; thus, communication between these cells plays an important role in homeostasis as well as in the pathophysiology of diseases in the lungs. For a better understanding of the pathophysiology of lung diseases, researchers have isolated each type of lung cell to investigate the changes in their gene expressions, including their humoral factor or adhesion molecules, to reveal the intercellular communication among these cells. In particular, investigations during the past decade have focused on extracellular vesicles, which are lipid bilayer delimited vesicles released from a cell that can move among various cells and transfer substances, including microRNAs, mRNAs and proteins, thus, functioning as intercellular messengers. Extracellular vesicles can be classified into three general groups: apoptotic bodies, exosomes, and microparticles. Extracellular vesicles, especially exosomes and microparticles, are attracting increasing attention from pulmonologists as tools for understanding pathogenesis and disease diagnosis. Here, we review studies, including our own, on exosomes and microparticles and their roles in both lung homeostasis and the pathogenesis of lung diseases such as idiopathic pulmonary fibrosis, chronic obstructive lung diseases, and acute respiratory distress syndrome. This review also addresses the roles of extracellular vesicles in COVID-19, the current global public health crisis. |COVID-19/*etiology[MESH] |Cell Communication[MESH] |Cell-Derived Microparticles[MESH] |Exosomes[MESH] |Extracellular Vesicles/classification/*physiology[MESH] |Homeostasis[MESH] |Humans[MESH] |Lung Diseases/*etiology[MESH] |Lung/*cytology/*metabolism[MESH] |MicroRNAs/metabolism[MESH] |Protein Transport[MESH]Extracellular vesicles: Their emerging roles in the pathogenesis of re(epmc).pdf DeepDyve Pubget Overpricing