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10.1016/j.apsb.2021.02.022 http://scihub22266oqcxt.onion/10.1016/j.apsb.2021.02.022 33747756!7955583!33747756     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33747756&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Acta+Pharm+Sin+B 2021 ; 11 (4): 852-870 Nephropedia Template TP {{tp|p=33747756|t=2021. Innate and adaptive immune responses toward nanomedicines |pdf=|usr=}}{{33747756}} gab.com Text Innate and adaptive immune responses toward nanomedicines JO: Acta Pharm Sin B http://www.kidney.de/pget.php?&tw=1&pmid=33747756 #FOAvip Since the commercialization of the first liposomes used for drug delivery, Doxil/Caelyx(R) and Myocet(R), tremendous progress has been made in understanding interactions between nanomedicines and biological systems. Fundamental work at the interface of engineering and medicine has allowed nanomedicines to deliver therapeutic small molecules and nucleic acids more efficiently. While nanomedicines are used in oncology for immunotherapy or to deliver combinations of cytotoxics, the clinical successes of gene silencing approaches like patisiran lipid complexes (Onpattro(R)) have paved the way for a variety of therapies beyond cancer. In parallel, the global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has highlighted the potential of mRNA vaccines to develop immunization strategies at unprecedented speed. To rationally design therapeutic and vaccines, chemists, materials scientists, and drug delivery experts need to better understand how nanotechnologies interact with the immune system. This review presents a comprehensive overview of the innate and adaptative immune systems and emphasizes the intricate mechanisms through which nanomedicines interact with these biological functions. Twit Text FOAVip Innate and adaptive immune responses toward nanomedicines ????Acta Pharm Sin B http://www.kidney.de/pget.php?&tw=1&pmid=33747756 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33747756 #FOAvip English Wikipedia <ref>{{Cite pmid|33747756}}</ref> Innate and adaptive immune responses toward nanomedicines #MMPMID33747756 Viana IMO; Roussel S; Defrene J; Lima EM; Barabe F; Bertrand N Acta Pharm Sin B 2021[Apr]; 11 (4): 852-870 PMID33747756show ga Since the commercialization of the first liposomes used for drug delivery, Doxil/Caelyx(R) and Myocet(R), tremendous progress has been made in understanding interactions between nanomedicines and biological systems. Fundamental work at the interface of engineering and medicine has allowed nanomedicines to deliver therapeutic small molecules and nucleic acids more efficiently. While nanomedicines are used in oncology for immunotherapy or to deliver combinations of cytotoxics, the clinical successes of gene silencing approaches like patisiran lipid complexes (Onpattro(R)) have paved the way for a variety of therapies beyond cancer. In parallel, the global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has highlighted the potential of mRNA vaccines to develop immunization strategies at unprecedented speed. To rationally design therapeutic and vaccines, chemists, materials scientists, and drug delivery experts need to better understand how nanotechnologies interact with the immune system. This review presents a comprehensive overview of the innate and adaptative immune systems and emphasizes the intricate mechanisms through which nanomedicines interact with these biological functions. äInnate and adaptive immune responses toward nanomedicines (epmc).pdf DeepDyve Pubget Overpricing