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COVID-19 highlights the model dilemma in biomedical research #MMPMID33747552
Adhikary PP; Ul Ain Q; Hocke AC; Hedtrich S
Nat Rev Mater 2021[]; 6 (5): 374-376 PMID33747552show ga
Scientists worldwide struggle to identify suitable animal models to study SARS-CoV-2 infections. Interspecies-related differences, such as host specificity, divergent immune responses, or the unavailability of species-specific reagents hamper the research. Human-based models, such as micro-engineered multi-organs-on-chip, may hold the solution.