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10.2302/kjm.2021-0003-OA

http://scihub22266oqcxt.onion/10.2302/kjm.2021-0003-OA
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33746151!ä!33746151

suck abstract from ncbi


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pmid33746151      Keio+J+Med 2021 ; 70 (2): 35-43
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  • RT-PCR Screening Tests for SARS-CoV-2 with Saliva Samples in Asymptomatic People: Strategy to Maintain Social and Economic Activities while Reducing the Risk of Spreading the Virus #MMPMID33746151
  • Oba J; Taniguchi H; Sato M; Takamatsu R; Morikawa S; Nakagawa T; Takaishi H; Saya H; Matsuo K; Nishihara H
  • Keio J Med 2021[Jun]; 70 (2): 35-43 PMID33746151show ga
  • The year 2020 will be remembered for the coronavirus disease 2019 (COVID-19) pandemic, which continues to affect the whole world. Early and accurate identification of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is fundamental to combat the disease. Among the current diagnostic tests, real-time reverse transcriptase-polymerase chain reaction (RT-qPCR) is the most reliable and frequently used method. Herein, we discuss the interpretation of RT-qPCR results relative to viral infectivity. Although nasopharyngeal swab samples are often used for RT-qPCR testing, they require collection by trained medical staff. Saliva samples are emerging as an inexpensive and efficient alternative for large-scale screening. Pooled-sample testing of saliva has been applied for mass screening of SARS-CoV-2 infection. Current policies recommend isolating people with borderline cycle threshold (Ct) values (35
  • |*Asymptomatic Infections[MESH]
  • |*SARS-CoV-2[MESH]
  • |COVID-19 Nucleic Acid Testing/*methods[MESH]
  • |COVID-19/*diagnosis/prevention & control[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Japan/epidemiology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Risk Reduction Behavior[MESH]


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