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10.1016/j.vaccine.2021.02.037

http://scihub22266oqcxt.onion/10.1016/j.vaccine.2021.02.037
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33744049!7894202!33744049
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suck abstract from ncbi


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pmid33744049      Vaccine 2021 ; 39 (15): 2165-2176
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  • The potential effects of deploying SARS-Cov-2 vaccines on cold storage capacity and immunization workload in countries of the WHO African Region #MMPMID33744049
  • Ortiz JR; Robertson J; Hsu JS; Yu SL; Driscoll AJ; Williams SR; Chen WH; Fitzpatrick MC; Sow S; Biellik RJ; Neuzil KM
  • Vaccine 2021[Apr]; 39 (15): 2165-2176 PMID33744049show ga
  • BACKGROUND: SARS-CoV-2 vaccines will be deployed to countries with limited immunization systems. METHODS: We assessed the effect of deploying SARS-Cov-2 vaccines on cold storage capacity and immunization workload in a simulated WHO African Region country using region-specific data on immunization, population, healthcare workers (HCWs), cold storage capacity (quartile values for national and subnational levels), and characteristics of an approved SARS-CoV-2 vaccine. We calculated monthly increases in vaccine doses, doses per vaccinator, and cold storage volumes for four-month SARS-CoV-2 vaccination campaigns targeting risk groups compared to routine immunization baselines. RESULTS: Administering SARS-CoV-2 vaccines to risk groups would increase total monthly doses by 27.0% for >/= 65 years, 91.7% for chronic diseases patients, and 1.1% for HCWs. Assuming median nurse density estimates adjusted for absenteeism and proportion providing immunization services, SARS-CoV-2 vaccination campaigns would increase total monthly doses per vaccinator by 29.3% for >/= 65 years, 99.6% for chronic diseases patients, and 1.2% for HCWs. When we applied quartiles of actual African Region country vaccine storage capacity, routine immunization vaccine volumes exceeded national-level storage capacity for at least 75% of countries, but subnational levels had sufficient storage capacity for SARS-CoV-2 vaccines for at least 75% of countries. CONCLUSIONS: In the WHO African Region, SARS-CoV-2 vaccination campaigns would substantially increase doses per vaccinator and cold storage capacity requirements over routine immunization baselines. Pandemic vaccination campaigns would increase storage requirements of national-level stores already at their limits, but sufficient capacity exists at subnational levels. Immediate attention to strengthening immunization systems is essential to support pandemic responses.
  • |*Refrigeration[MESH]
  • |*Workload[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Africa[MESH]
  • |Aged[MESH]
  • |COVID-19 Vaccines/*administration & dosage[MESH]
  • |COVID-19/*prevention & control[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Humans[MESH]
  • |Immunization Programs/*organization & administration[MESH]
  • |Middle Aged[MESH]
  • |Vaccination[MESH]
  • |World Health Organization[MESH]


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