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10.1038/s41467-021-22036-z http://scihub22266oqcxt.onion/10.1038/s41467-021-22036-z 33741972!7979809!33741972     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\33741972.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nat+Commun 2021 ; 12 (1): 1724 Nephropedia Template TP {{tp|p=33741972|t=2021. Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection |pdf=|usr=}}{{33741972}} gab.com Text Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=33741972 #FOAvip T-cell immunity is important for recovery from COVID-19 and provides heightened immunity for re-infection. However, little is known about the SARS-CoV-2-specific T-cell immunity in virus-exposed individuals. Here we report virus-specific CD4(+) and CD8(+) T-cell memory in recovered COVID-19 patients and close contacts. We also demonstrate the size and quality of the memory T-cell pool of COVID-19 patients are larger and better than those of close contacts. However, the proliferation capacity, size and quality of T-cell responses in close contacts are readily distinguishable from healthy donors, suggesting close contacts are able to gain T-cell immunity against SARS-CoV-2 despite lacking a detectable infection. Additionally, asymptomatic and symptomatic COVID-19 patients contain similar levels of SARS-CoV-2-specific T-cell memory. Overall, this study demonstrates the versatility and potential of memory T cells from COVID-19 patients and close contacts, which may be important for host protection. Twit Text FOAVip Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=33741972 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33741972 #FOAvip English Wikipedia <ref>{{Cite pmid|33741972}}</ref> Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection #MMPMID33741972 Wang Z; Yang X; Zhong J; Zhou Y; Tang Z; Zhou H; He J; Mei X; Tang Y; Lin B; Chen Z; McCluskey J; Yang J; Corbett AJ; Ran P Nat Commun 2021[Mar]; 12 (1): 1724 PMID33741972show ga T-cell immunity is important for recovery from COVID-19 and provides heightened immunity for re-infection. However, little is known about the SARS-CoV-2-specific T-cell immunity in virus-exposed individuals. Here we report virus-specific CD4(+) and CD8(+) T-cell memory in recovered COVID-19 patients and close contacts. We also demonstrate the size and quality of the memory T-cell pool of COVID-19 patients are larger and better than those of close contacts. However, the proliferation capacity, size and quality of T-cell responses in close contacts are readily distinguishable from healthy donors, suggesting close contacts are able to gain T-cell immunity against SARS-CoV-2 despite lacking a detectable infection. Additionally, asymptomatic and symptomatic COVID-19 patients contain similar levels of SARS-CoV-2-specific T-cell memory. Overall, this study demonstrates the versatility and potential of memory T cells from COVID-19 patients and close contacts, which may be important for host protection. |Antibodies, Viral/immunology[MESH] |Asymptomatic Infections[MESH] |CD4-Positive T-Lymphocytes/*immunology[MESH] |CD8-Positive T-Lymphocytes/*immunology[MESH] |COVID-19/blood/*immunology[MESH] |Case-Control Studies[MESH] |Humans[MESH] |Immunologic Memory/*immunology[MESH] |Interferon-gamma/biosynthesis/immunology[MESH] |SARS-CoV-2/*immunology[MESH]Exposure to SARS-CoV-2 generates T-cell memory in the absence of a det(epmc).pdf DeepDyve Pubget Overpricing