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10.1016/j.acra.2021.03.001

http://scihub22266oqcxt.onion/10.1016/j.acra.2021.03.001
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33741210!7936551!33741210
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suck abstract from ncbi


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pmid33741210      Acad+Radiol 2021 ; 28 (8): 1048-1057
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  • Quantification of COVID-19 Opacities on Chest CT - Evaluation of a Fully Automatic AI-approach to Noninvasively Differentiate Critical Versus Noncritical Patients #MMPMID33741210
  • Mader C; Bernatz S; Michalik S; Koch V; Martin SS; Mahmoudi S; Basten L; Grunewald LD; Bucher A; Albrecht MH; Vogl TJ; Booz C
  • Acad Radiol 2021[Aug]; 28 (8): 1048-1057 PMID33741210show ga
  • OBJECTIVES: To evaluate the potential of a fully automatic artificial intelligence (AI)-driven computed tomography (CT) software prototype to quantify severity of COVID-19 infection on chest CT in relationship with clinical and laboratory data. METHODS: We retrospectively analyzed 50 patients with laboratory confirmed COVID-19 infection who had received chest CT between March and July 2020. Pulmonary opacifications were automatically evaluated by an AI-driven software and correlated with clinical and laboratory parameters using Spearman-Rho and linear regression analysis. We divided the patients into sub cohorts with or without necessity of intensive care unit (ICU) treatment. Sub cohort differences were evaluated employing Wilcoxon-Mann-Whitney-Test. RESULTS: We included 50 CT examinations (mean age, 57.24 years), of whom 24 (48%) had an ICU stay. Extent of COVID-19 like opacities on chest CT showed correlations (all p < 0.001 if not otherwise stated) with occurrence of ICU stay (R?=?0.74), length of ICU stay (R?=?0.81), lethal outcome (R?=?0.56) and length of hospital stay (R?=?0.33, p < 0.05). The opacities extent was correlated with laboratory parameters: neutrophil count (NEU) (R?=?0.60), lactate dehydrogenase (LDH) (R?=?0.60), troponin (TNTHS) (R?=?0.55) and c-reactive protein (CRP) (R?=?0.51). Differences (p < 0.001) between ICU group and non-ICU group concerned longer length of hospital stay (24.04 vs. 10.92 days), higher opacity score (12.50 vs. 4.96) and severity of laboratory data changes such as c-reactive protein (11.64 vs. 5.07 mg/dl, p < 0.01). CONCLUSIONS: Automatically AI-driven quantification of opacities on chest CT correlates with laboratory and clinical data in patients with confirmed COVID-19 infection and may serve as non-invasive predictive marker for clinical course of COVID-19.
  • |*Artificial Intelligence[MESH]
  • |*COVID-19/diagnostic imaging[MESH]
  • |*Tomography, X-Ray Computed[MESH]
  • |Humans[MESH]
  • |Lung[MESH]
  • |Middle Aged[MESH]


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