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10.1002/jmv.26950

http://scihub22266oqcxt.onion/10.1002/jmv.26950
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33738829!8250980!33738829
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suck abstract from ncbi


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pmid33738829      J+Med+Virol 2021 ; 93 (7): 4351-4357
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  • Performances of the VitaPCR SARS-CoV-2 Assay during the second wave of the COVID-19 epidemic in France #MMPMID33738829
  • Fitoussi F; Dupont R; Tonen-Wolyec S; Belec L
  • J Med Virol 2021[Jul]; 93 (7): 4351-4357 PMID33738829show ga
  • To assess the practicability (usability and satisfaction) and analytical performances of the VitaPCR SARS-CoV-2 Assay (Credo Diagnostics Biomedical Pte. Ltd.), a rapid point-of-care nucleic acid amplification test (NAAT), by reference to real-time reverse-transcription polymerase chain reaction (rRT-PCR) for respiratory viruses. The practicability of the VitaPCR Assay and Instrument was assessed from usability evaluation and a satisfaction questionnaire. Nasopharyngeal swabs were collected from 239 patients with coronavirus disease 2019 (COVID-19)-like illness during the second epidemic wave, in Paris, France. Overall, the usability of the VitaPCR Instrument was high. The satisfaction questionnaire indicated a high appreciation of the VitaPCR NAAT mainly for the short duration of analysis in only 20 min. A total of 140 and 99 samples were positive and negative for SARS-CoV-2 RNA by rRT-PCR, respectively. In the event of significant viral load (i.e., N gene C(t) values 33), the platform's analytical performances dropped significantly, with lower sensitivity, concordance, and accuracy, while its specificity remained high. The VitaPCR SARS-CoV-2 Assay is an accurate rapid point-of-care NAAT, suitable for clinical practice for the rapid diagnosis of COVID-19, especially in patients with COVID-19-suspected symptoms.
  • |COVID-19 Testing/*methods[MESH]
  • |COVID-19/*diagnosis/epidemiology[MESH]
  • |Coronavirus Envelope Proteins/genetics[MESH]
  • |Coronavirus Nucleocapsid Proteins/genetics[MESH]
  • |Coronavirus RNA-Dependent RNA Polymerase/genetics[MESH]
  • |France/epidemiology[MESH]
  • |Humans[MESH]
  • |Nucleic Acid Amplification Techniques/*methods[MESH]
  • |Phosphoproteins/genetics[MESH]
  • |Point-of-Care Testing[MESH]
  • |Prospective Studies[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction/*methods[MESH]
  • |SARS-CoV-2/*genetics[MESH]
  • |Sensitivity and Specificity[MESH]
  • |Surveys and Questionnaires[MESH]


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