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10.1016/j.bj.2020.12.007

http://scihub22266oqcxt.onion/10.1016/j.bj.2020.12.007
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suck abstract from ncbi


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pmid33736952      Biomed+J 2021 ; 44 (1): 101-104
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  • Comparison of the Roche cobas 6800 SARS-CoV-2 test and the Taiwan CDC protocol for the molecular diagnosis of COVID-19 #MMPMID33736952
  • You HL; Lin MC; Lee CH
  • Biomed J 2021[Mar]; 44 (1): 101-104 PMID33736952show ga
  • The current coronavirus disease 2019 (COVID-19) pandemic has caused significant challenges throughout the world and a rapid, reliable diagnostic test is in high demand. Real-time reverse transcription polymerase chain reaction (RT-PCR) was one of the most quickly established methods of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection and is considered to be the gold standard. In this report, we share our experience of using two different testing platforms: the cobas 6800 SARS-CoV-2 test, an automated system that was recently granted Emergency Use Authorization by the FDA, and a laboratory-developed test based on the protocol from the Taiwan Centers for Disease Control (CDC). There was an overall 96.2% agreement between the two platforms. However, the positive agreement between the two platforms was only 80.0%. We found 3 instances of discordance between the two systems and this emphasized the need for timely diagnosis with a reliable testing platform.
  • |COVID-19 Nucleic Acid Testing[MESH]
  • |COVID-19 Testing/*methods[MESH]
  • |COVID-19/*diagnosis[MESH]
  • |Clinical Protocols[MESH]
  • |Coronavirus RNA-Dependent RNA Polymerase/genetics[MESH]
  • |Humans[MESH]
  • |Molecular Diagnostic Techniques/*methods[MESH]
  • |Nucleocapsid/genetics[MESH]
  • |SARS-CoV-2/*genetics[MESH]
  • |Taiwan[MESH]


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