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pmid33734072      Ugeskr+Laeger 2021 ; 183 (11): ä
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  • Development and use of vaccines from the 18th century to the SARS-CoV 2 period #MMPMID33734072
  • Skinhoj P; Bygbjerg IC
  • Ugeskr Laeger 2021[Mar]; 183 (11): ä PMID33734072show ga
  • This review is about the development and use of vaccines from the early smallpox vaccine in the 18th century to the forthcoming SARS-CoV 2 vaccines. Immunisations have been of paramount importance for childhood mortality and public health in general, but some obstacles have also been encountered such as vaccine failures and vaccine scepticism. This calls for continued emphasis on large phase three studies not only for demonstration of efficacy but also for safety and possible side effects. The rapid approval of SARS-CoV 2 vaccines requires special attention.
  • |*COVID-19 Vaccines[MESH]
  • |COVID-19/*prevention & control[MESH]
  • |Child[MESH]
  • |History, 18th Century[MESH]
  • |History, 19th Century[MESH]
  • |History, 20th Century[MESH]
  • |History, 21st Century[MESH]
  • |Humans[MESH]
  • |SARS-CoV-2[MESH]
  • |Smallpox Vaccine/administration & dosage/*history[MESH]


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